LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180614_BG_03 | 1612 | 0.0523 | 51 | 36 | 14 | 13 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_6 | 87 | 0.0512 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03121 | 0.1499 |
| Neratinib | 180614_BG_04 | 3017 | 0.0563 | 125 | 52 | 6 | 10 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_7 | 177 | 0.0554 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03542 | 0.3321 |
| Neratinib | 180614_BG_04 | 2730 | 0.0411 | 42 | 72 | 7 | 3 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_8 | 114 | 0.0401 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02009 | 0.3012 |
| Neratinib | 180614_BG_04 | 2847 | 0.0516 | 101 | 51 | 7 | 7 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_9 | 152 | 0.0507 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03069 | 0.3140 |
| Neratinib | 180614_BG_02 | 1121 | 0.1572 | 5 | 172 | 4 | 22 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_1 | 177 | 0.1364 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.11637 | 0.0559 |
| Neratinib | 180614_BG_02 | 1158 | 0.1775 | 25 | 185 | 5 | 19 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_2 | 210 | 0.1535 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.13351 | 0.0640 |
| Neratinib | 180614_BG_02 | 1320 | 0.1313 | 36 | 142 | 9 | 9 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_3 | 178 | 0.1188 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.09883 | 0.0972 |
| Neratinib | 180614_BG_03 | 1308 | 0.1391 | 72 | 120 | 5 | 12 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_4 | 192 | 0.1280 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.10800 | 0.0948 |
| Neratinib | 180614_BG_03 | 1375 | 0.0984 | 37 | 102 | 8 | 19 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_5 | 139 | 0.0918 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07181 | 0.1078 |
| Neratinib | 180614_BG_03 | 1371 | 0.1005 | 42 | 100 | 9 | 20 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_6 | 142 | 0.0939 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07386 | 0.1070 |
| Neratinib | 180614_BG_04 | 1627 | 0.0511 | 36 | 49 | 4 | 22 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_7 | 85 | 0.0496 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02965 | 0.1524 |
| Neratinib | 180614_BG_04 | 1419 | 0.0983 | 77 | 70 | 8 | 14 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_8 | 147 | 0.0939 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07387 | 0.1160 |
| Neratinib | 180614_BG_04 | 1667 | 0.1143 | 91 | 110 | 13 | 14 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_9 | 201 | 0.1076 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.08761 | 0.1590 |
| Taxol | 180614_BG_02 | 17244 | 0.0174 | 26 | 274 | 7 | 15 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_1 | 300 | 0.0171 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00290 | 1.0052 |
| Taxol | 180614_BG_02 | 17049 | 0.0180 | 35 | 273 | 12 | 5 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_2 | 308 | 0.0177 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00225 | 0.9999 |
| Taxol | 180614_BG_02 | 16768 | 0.0226 | 39 | 340 | 13 | 7 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_3 | 379 | 0.0221 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00211 | 0.9921 |
| Taxol | 180614_BG_03 | 17286 | 0.0205 | 72 | 284 | 6 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_4 | 356 | 0.0202 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00018 | 1.0063 |
| Taxol | 180614_BG_03 | 17719 | 0.0215 | 70 | 312 | 8 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_5 | 382 | 0.0211 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00111 | 1.0180 |
| Taxol | 180614_BG_03 | 17225 | 0.0205 | 97 | 258 | 13 | 17 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_6 | 355 | 0.0202 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00020 | 1.0047 |
| Taxol | 180614_BG_04 | 18063 | 0.0199 | 70 | 290 | 9 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_7 | 360 | 0.0195 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00045 | 1.0272 |
| Taxol | 180614_BG_04 | 17665 | 0.0223 | 93 | 303 | 10 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_8 | 396 | 0.0219 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00193 | 1.0166 |
| Taxol | 180614_BG_04 | 17284 | 0.0174 | 61 | 241 | 13 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_9 | 302 | 0.0172 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00282 | 1.0063 |
| Taxol | 180614_BG_02 | 15551 | 0.0284 | 57 | 386 | 3 | 16 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_1 | 443 | 0.0277 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00770 | 0.9572 |
| Taxol | 180614_BG_02 | 14760 | 0.0302 | 64 | 383 | 12 | 7 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_2 | 447 | 0.0294 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00940 | 0.9333 |
| Taxol | 180614_BG_02 | 14918 | 0.0291 | 53 | 382 | 14 | 5 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_3 | 435 | 0.0283 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00834 | 0.9382 |