Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1954 | USP7-IN-1 | 0.316 | 0.8617 | 0.00088 |
| HCC1954 | USP7-IN-1 | 0.999279741 | 1.2305 | 0.00798 |
| HCC1954 | USP7-IN-1 | 3.16 | 0.9468 | 0.02449 |
| HCC1954 | USP7-IN-1 | 9.992797406 | 0.9085 | -0.00604 |
| HCC1954 | USP7-IN-1 | 31.6 | 0.8885 | -0.01299 |
| HCC1954 | USP7-IN-1 | 50.0 | 0.8323 | -0.01610 |
| HCC1954 | Doxycycline | 0.009992797 | 0.8381 | 0.02769 |
| HCC1954 | Doxycycline | 0.0316 | 0.8683 | 0.03227 |
| HCC1954 | Doxycycline | 0.099927974 | 0.9199 | -0.02041 |
| HCC1954 | Doxycycline | 0.316 | 1.0995 | 0.01155 |
| HCC1954 | Doxycycline | 0.999279741 | 0.9231 | -0.00869 |
| HCC1954 | Doxycycline | 3.16 | 0.9377 | -0.00275 |
| HCC1954 | Doxycycline | 9.992797406 | 1.8142 | 0.08673 |
| HCC1954 | Doxycycline | 31.6 | 0.1237 | 0.10650 |
| HCC1954 | Doxycycline | 50.0 | 0.0566 | 0.00247 |
| HCC1954 | GW7647 | 0.009992797 | 1.0210 | -0.00780 |
| HCC1954 | GW7647 | 0.0316 | 0.9770 | 0.02094 |
| HCC1954 | GW7647 | 0.099927974 | 1.0799 | 0.00153 |
| HCC1954 | GW7647 | 0.316 | 0.8929 | 0.02009 |
| HCC1954 | GW7647 | 0.999279741 | 1.0122 | -0.01267 |
| HCC1954 | GW7647 | 3.16 | 1.0752 | -0.00005 |
| HCC1954 | GW7647 | 9.992797406 | 1.1672 | -0.01621 |
| HCC1954 | GW7647 | 31.6 | 1.2032 | -0.01590 |
| HCC1954 | GW7647 | 50.0 | 0.5700 | 0.10777 |
| HCC1954 | HBX19818 | 0.009992797 | 0.9357 | -0.00672 |