Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1954 | Sepantronium | 0.0316 | -0.1883 | 0.45900 |
| HCC1954 | Sepantronium | 0.099927974 | -0.4240 | 0.57806 |
| HCC1954 | Sepantronium | 0.316 | -0.4942 | 0.63623 |
| HCC1954 | Sepantronium | 0.999279741 | -0.6344 | 0.64885 |
| HCC1954 | Sepantronium | 3.16 | -0.6230 | 0.69394 |
| HCC1954 | Sepantronium | 9.992797406 | -0.6825 | 0.68043 |
| HCC1954 | Sepantronium | 31.6 | -0.6509 | 0.69292 |
| HCC1954 | Sepantronium | 50.0 | -0.7271 | 0.45008 |
| HCC1954 | z-VAE(OMe)-fmk | 0.009992797 | 0.9941 | 0.00651 |
| HCC1954 | z-VAE(OMe)-fmk | 0.0316 | 0.8929 | -0.00956 |
| HCC1954 | z-VAE(OMe)-fmk | 0.099927974 | 1.0426 | 0.00834 |
| HCC1954 | z-VAE(OMe)-fmk | 0.316 | 0.9337 | 0.00814 |
| HCC1954 | z-VAE(OMe)-fmk | 0.999279741 | 0.9625 | -0.00747 |
| HCC1954 | z-VAE(OMe)-fmk | 3.16 | 0.9117 | 0.02500 |
| HCC1954 | z-VAE(OMe)-fmk | 9.992797406 | 0.9114 | -0.02507 |
| HCC1954 | z-VAE(OMe)-fmk | 31.6 | 1.0760 | 0.01147 |
| HCC1954 | z-VAE(OMe)-fmk | 50.0 | 1.0513 | -0.01352 |
| HCC202 | 1247825-37-1 | 0.009992797 | 1.0496 | 0.00773 |
| HCC202 | 1247825-37-1 | 0.0316 | 1.0413 | -0.00106 |
| HCC202 | 1247825-37-1 | 0.099927974 | 1.0094 | 0.01990 |
| HCC202 | 1247825-37-1 | 0.316 | 1.2197 | -0.01316 |
| HCC202 | 1247825-37-1 | 0.999279741 | 1.1075 | -0.00456 |
| HCC202 | 1247825-37-1 | 3.16 | 0.9860 | 0.00358 |
| HCC202 | 1247825-37-1 | 9.992797406 | 0.3771 | 0.03818 |
| HCC202 | 1247825-37-1 | 31.6 | -0.2330 | 0.26421 |