Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1806 | Pevonedistat | 0.316 | -0.2347 | 0.45625 |
| HCC1806 | Pevonedistat | 0.999279741 | -0.2294 | 0.49151 |
| HCC1806 | Pevonedistat | 3.16 | -0.2253 | 0.50851 |
| HCC1806 | Pevonedistat | 9.992797406 | -0.2191 | 0.51156 |
| HCC1806 | Pevonedistat | 31.6 | -0.2681 | 0.53094 |
| HCC1806 | Pevonedistat | 50.0 | -0.2883 | 0.37418 |
| HCC1806 | P22077 | 0.009992797 | 0.9649 | 0.00140 |
| HCC1806 | P22077 | 0.0316 | 1.0221 | -0.00075 |
| HCC1806 | P22077 | 0.099927974 | 1.0013 | 0.00090 |
| HCC1806 | P22077 | 0.316 | 0.9675 | 0.00110 |
| HCC1806 | P22077 | 0.999279741 | 0.9818 | -0.00197 |
| HCC1806 | P22077 | 3.16 | 0.9686 | 0.03257 |
| HCC1806 | P22077 | 9.992797406 | 0.5143 | 0.34008 |
| HCC1806 | P22077 | 31.6 | -0.3386 | 0.61361 |
| HCC1806 | P22077 | 50.0 | -0.4514 | 0.20967 |
| HCC1806 | PB49673382 | 0.009992797 | 1.0007 | 0.00096 |
| HCC1806 | PB49673382 | 0.0316 | 0.9964 | -0.00324 |
| HCC1806 | PB49673382 | 0.099927974 | 0.9930 | 0.00085 |
| HCC1806 | PB49673382 | 0.316 | 0.9601 | -0.00177 |
| HCC1806 | PB49673382 | 0.999279741 | 0.9399 | -0.00123 |
| HCC1806 | PB49673382 | 3.16 | 0.7721 | 0.00065 |
| HCC1806 | PB49673382 | 9.992797406 | 0.3570 | 0.02212 |
| HCC1806 | PB49673382 | 31.6 | 0.1874 | 0.04138 |
| HCC1806 | PB49673382 | 50.0 | 0.1357 | 0.02930 |
| HCC1806 | Pimozide | 0.009992797 | 0.9963 | -0.00123 |