Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1806 | USP7-IN-1 | 0.999279741 | 0.9492 | 0.00111 |
| HCC1806 | USP7-IN-1 | 3.16 | 1.0026 | -0.00047 |
| HCC1806 | USP7-IN-1 | 9.992797406 | 0.9643 | 0.00297 |
| HCC1806 | USP7-IN-1 | 31.6 | 0.8978 | -0.00173 |
| HCC1806 | USP7-IN-1 | 50.0 | 0.8197 | 0.00847 |
| HCC1806 | Doxycycline | 0.009992797 | 0.9293 | 0.00518 |
| HCC1806 | Doxycycline | 0.0316 | 0.9861 | 0.00272 |
| HCC1806 | Doxycycline | 0.099927974 | 0.9680 | -0.00140 |
| HCC1806 | Doxycycline | 0.316 | 1.0227 | -0.00225 |
| HCC1806 | Doxycycline | 0.999279741 | 0.9813 | -0.00151 |
| HCC1806 | Doxycycline | 3.16 | 0.9614 | -0.00081 |
| HCC1806 | Doxycycline | 9.992797406 | 0.8193 | 0.10205 |
| HCC1806 | Doxycycline | 31.6 | 0.0383 | 0.31884 |
| HCC1806 | Doxycycline | 50.0 | -0.1768 | 0.12312 |
| HCC1806 | GW7647 | 0.009992797 | 1.0149 | -0.00088 |
| HCC1806 | GW7647 | 0.0316 | 0.9941 | 0.00478 |
| HCC1806 | GW7647 | 0.099927974 | 1.0009 | -0.00219 |
| HCC1806 | GW7647 | 0.316 | 1.0120 | 0.00012 |
| HCC1806 | GW7647 | 0.999279741 | 1.0313 | 0.00244 |
| HCC1806 | GW7647 | 3.16 | 0.9881 | 0.00122 |
| HCC1806 | GW7647 | 9.992797406 | 0.9879 | 0.00172 |
| HCC1806 | GW7647 | 31.6 | 0.4479 | 0.04588 |
| HCC1806 | GW7647 | 50.0 | -0.1520 | 0.33496 |
| HCC1806 | HBX19818 | 0.009992797 | 1.0358 | -0.00015 |
| HCC1806 | HBX19818 | 0.0316 | 1.0081 | 0.00021 |