Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1500 | z-VAE(OMe)-fmk | 9.992797406 | 0.9147 | -0.00482 |
| HCC1500 | z-VAE(OMe)-fmk | 31.6 | 1.1021 | 0.00992 |
| HCC1500 | z-VAE(OMe)-fmk | 50.0 | 1.1104 | -0.04116 |
| HCC1806 | 1247825-37-1 | 0.009992797 | 0.9988 | -0.00166 |
| HCC1806 | 1247825-37-1 | 0.0316 | 1.0536 | -0.00151 |
| HCC1806 | 1247825-37-1 | 0.099927974 | 0.9907 | 0.00193 |
| HCC1806 | 1247825-37-1 | 0.316 | 0.9723 | 0.00228 |
| HCC1806 | 1247825-37-1 | 0.999279741 | 0.9193 | 0.00021 |
| HCC1806 | 1247825-37-1 | 3.16 | 0.8950 | 0.00791 |
| HCC1806 | 1247825-37-1 | 9.992797406 | 0.4577 | 0.06760 |
| HCC1806 | 1247825-37-1 | 31.6 | -0.2393 | 0.34018 |
| HCC1806 | 1247825-37-1 | 50.0 | -0.2678 | 0.38456 |
| HCC1806 | b-AP15 | 0.009992797 | 0.9875 | 0.00340 |
| HCC1806 | b-AP15 | 0.0316 | 0.9554 | -0.00101 |
| HCC1806 | b-AP15 | 0.099927974 | 0.8023 | 0.02344 |
| HCC1806 | b-AP15 | 0.316 | 0.0186 | 0.26633 |
| HCC1806 | b-AP15 | 0.999279741 | -0.3249 | 0.55132 |
| HCC1806 | b-AP15 | 3.16 | -0.2462 | 0.44494 |
| HCC1806 | b-AP15 | 9.992797406 | -0.3760 | 0.59579 |
| HCC1806 | b-AP15 | 31.6 | -0.5022 | 0.76943 |
| HCC1806 | b-AP15 | 50.0 | -0.3342 | 0.63046 |
| HCC1806 | USP7-IN-1 | 0.009992797 | 1.0124 | 0.00058 |
| HCC1806 | USP7-IN-1 | 0.0316 | 0.9942 | 0.00196 |
| HCC1806 | USP7-IN-1 | 0.099927974 | 0.9778 | 0.00120 |
| HCC1806 | USP7-IN-1 | 0.316 | 1.0018 | 0.00653 |