Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC1428 Pimozide
0.099927974
 0.9971 0.00044
HCC1428 Pimozide
0.316
 0.8304 0.00291
HCC1428 Pimozide
0.999279741
 0.7913 0.00933
HCC1428 Pimozide
3.16
 0.8022 0.01900
HCC1428 Pimozide
9.992797406
 0.1404 0.17627
HCC1428 Pimozide
31.6
 -0.6535 0.63335
HCC1428 Pimozide
50.0
 -0.7126 0.68826
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9187 -0.00682
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.8345 0.00151
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 0.9121 0.00158
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 0.9575 -0.00026
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.8864 -0.00344
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.7466 0.01317
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 1.0619 -0.00202
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9183 -0.00773
HCC1428 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.0123 -0.00248
HCC1428 SB1-F-21
0.009992797
 0.8885 0.00623
HCC1428 SB1-F-21
0.0316
 0.9839 -0.01152
HCC1428 SB1-F-21
0.099927974
 1.1207 -0.00536
HCC1428 SB1-F-21
0.316
 0.5010 0.08390
HCC1428 SB1-F-21
0.999279741
 -0.0454 0.32509
HCC1428 SB1-F-21
3.16
 -0.5145 0.58972
HCC1428 SB1-F-21
9.992797406
 -0.7047 0.72826
HCC1428 SB1-F-21
31.6
 -0.7391 0.70327
HCC1428 SB1-F-21
50.0
 -0.7458 0.53307