Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| BT-549 | Degrasyn | 0.0316 | 0.9885 | 0.00386 |
| BT-549 | Degrasyn | 0.099927974 | 0.9930 | -0.00168 |
| BT-549 | Degrasyn | 0.316 | 1.0074 | -0.00523 |
| BT-549 | Degrasyn | 0.999279741 | 0.9464 | 0.00480 |
| BT-549 | Degrasyn | 3.16 | 0.0025 | 0.18926 |
| BT-549 | Degrasyn | 9.992797406 | -0.3337 | 0.48329 |
| BT-549 | Degrasyn | 31.6 | -0.2544 | 0.35996 |
| BT-549 | Degrasyn | 50.0 | -0.2145 | 0.34159 |
| BT-549 | Sepantronium | 0.009992797 | 0.9599 | 0.02798 |
| BT-549 | Sepantronium | 0.0316 | 0.3523 | 0.13690 |
| BT-549 | Sepantronium | 0.099927974 | -0.1315 | 0.33265 |
| BT-549 | Sepantronium | 0.316 | -0.3114 | 0.51685 |
| BT-549 | Sepantronium | 0.999279741 | -0.3646 | 0.48118 |
| BT-549 | Sepantronium | 3.16 | -0.3608 | 0.55116 |
| BT-549 | Sepantronium | 9.992797406 | -0.3974 | 0.53472 |
| BT-549 | Sepantronium | 31.6 | -0.3729 | 0.51430 |
| BT-549 | Sepantronium | 50.0 | -0.4073 | 0.52002 |
| BT-549 | z-VAE(OMe)-fmk | 0.009992797 | 0.9898 | -0.00132 |
| BT-549 | z-VAE(OMe)-fmk | 0.0316 | 0.9845 | -0.00484 |
| BT-549 | z-VAE(OMe)-fmk | 0.099927974 | 1.0128 | -0.00008 |
| BT-549 | z-VAE(OMe)-fmk | 0.316 | 0.9736 | 0.00012 |
| BT-549 | z-VAE(OMe)-fmk | 0.999279741 | 0.9719 | -0.00070 |
| BT-549 | z-VAE(OMe)-fmk | 3.16 | 0.9876 | 0.00122 |
| BT-549 | z-VAE(OMe)-fmk | 9.992797406 | 0.9604 | -0.00346 |
| BT-549 | z-VAE(OMe)-fmk | 31.6 | 0.9727 | -0.00016 |