Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| BT-549 | b-AP15 | 0.316 | -0.1194 | 0.28645 |
| BT-549 | b-AP15 | 0.999279741 | -0.2718 | 0.38193 |
| BT-549 | b-AP15 | 3.16 | -0.3383 | 0.44464 |
| BT-549 | b-AP15 | 9.992797406 | -0.3838 | 0.59066 |
| BT-549 | b-AP15 | 31.6 | -0.3599 | 0.56541 |
| BT-549 | b-AP15 | 50.0 | -0.3183 | 0.51944 |
| BT-549 | USP7-IN-1 | 0.009992797 | 1.0460 | 0.00018 |
| BT-549 | USP7-IN-1 | 0.0316 | 1.0198 | -0.00258 |
| BT-549 | USP7-IN-1 | 0.099927974 | 0.9591 | -0.00194 |
| BT-549 | USP7-IN-1 | 0.316 | 1.0090 | 0.00228 |
| BT-549 | USP7-IN-1 | 0.999279741 | 0.9807 | 0.00886 |
| BT-549 | USP7-IN-1 | 3.16 | 0.9909 | -0.00097 |
| BT-549 | USP7-IN-1 | 9.992797406 | 0.9687 | 0.00078 |
| BT-549 | USP7-IN-1 | 31.6 | 0.9340 | 0.01168 |
| BT-549 | USP7-IN-1 | 50.0 | 0.8209 | 0.03763 |
| BT-549 | Doxycycline | 0.009992797 | 0.8937 | 0.01227 |
| BT-549 | Doxycycline | 0.0316 | 0.9870 | -0.00398 |
| BT-549 | Doxycycline | 0.099927974 | 0.9696 | 0.00064 |
| BT-549 | Doxycycline | 0.316 | 1.0033 | -0.00240 |
| BT-549 | Doxycycline | 0.999279741 | 0.9946 | -0.01065 |
| BT-549 | Doxycycline | 3.16 | 0.9261 | -0.00499 |
| BT-549 | Doxycycline | 9.992797406 | 0.8086 | 0.09271 |
| BT-549 | Doxycycline | 31.6 | 0.0191 | 0.23863 |
| BT-549 | Doxycycline | 50.0 | -0.1425 | 0.11852 |
| BT-549 | GW7647 | 0.009992797 | 0.9735 | -0.00051 |