Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-231 | ML-323 | 50.0 | 0.5091 | 0.00561 |
| MDA-MB-231 | Pevonedistat | 0.009992797 | 1.0191 | 0.00863 |
| MDA-MB-231 | Pevonedistat | 0.0316 | 0.9757 | 0.00427 |
| MDA-MB-231 | Pevonedistat | 0.099927974 | 0.9456 | 0.00143 |
| MDA-MB-231 | Pevonedistat | 0.316 | 0.4503 | 0.03260 |
| MDA-MB-231 | Pevonedistat | 0.999279741 | 0.0253 | 0.14909 |
| MDA-MB-231 | Pevonedistat | 3.16 | -0.0449 | 0.25062 |
| MDA-MB-231 | Pevonedistat | 9.992797406 | -0.0991 | 0.33028 |
| MDA-MB-231 | Pevonedistat | 31.6 | -0.1844 | 0.40197 |
| MDA-MB-231 | Pevonedistat | 50.0 | -0.2071 | 0.43454 |
| MDA-MB-231 | P22077 | 0.009992797 | 1.0307 | -0.00131 |
| MDA-MB-231 | P22077 | 0.0316 | 0.9632 | -0.00307 |
| MDA-MB-231 | P22077 | 0.099927974 | 1.0755 | 0.00170 |
| MDA-MB-231 | P22077 | 0.316 | 1.0184 | -0.00713 |
| MDA-MB-231 | P22077 | 0.999279741 | 1.0294 | -0.00187 |
| MDA-MB-231 | P22077 | 3.16 | 0.8253 | 0.00734 |
| MDA-MB-231 | P22077 | 9.992797406 | 0.8265 | 0.21944 |
| MDA-MB-231 | P22077 | 31.6 | -0.2862 | 0.41092 |
| MDA-MB-231 | P22077 | 50.0 | -0.4168 | 0.21527 |
| MDA-MB-231 | PB49673382 | 0.009992797 | 1.0727 | -0.00427 |
| MDA-MB-231 | PB49673382 | 0.0316 | 1.0215 | -0.00426 |
| MDA-MB-231 | PB49673382 | 0.099927974 | 1.0190 | -0.00440 |
| MDA-MB-231 | PB49673382 | 0.316 | 0.9794 | -0.00433 |
| MDA-MB-231 | PB49673382 | 0.999279741 | 1.0453 | -0.00155 |
| MDA-MB-231 | PB49673382 | 3.16 | 1.0663 | -0.00571 |