Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MCF7 | Pevonedistat | 0.009992797 | 0.9934 | 0.00406 |
| MCF7 | Pevonedistat | 0.0316 | 0.9010 | 0.00933 |
| MCF7 | Pevonedistat | 0.099927974 | 0.6159 | 0.03023 |
| MCF7 | Pevonedistat | 0.316 | 0.2733 | 0.06333 |
| MCF7 | Pevonedistat | 0.999279741 | 0.0898 | 0.07392 |
| MCF7 | Pevonedistat | 3.16 | 0.0061 | 0.07421 |
| MCF7 | Pevonedistat | 9.992797406 | 0.0169 | 0.07627 |
| MCF7 | Pevonedistat | 31.6 | 0.0001 | 0.10404 |
| MCF7 | Pevonedistat | 50.0 | -0.0374 | 0.11638 |
| MCF7 | P22077 | 0.009992797 | 1.0718 | -0.00018 |
| MCF7 | P22077 | 0.0316 | 0.9834 | -0.00201 |
| MCF7 | P22077 | 0.099927974 | 1.0160 | -0.00274 |
| MCF7 | P22077 | 0.316 | 1.0186 | -0.00120 |
| MCF7 | P22077 | 0.999279741 | 1.0181 | -0.00100 |
| MCF7 | P22077 | 3.16 | 0.9760 | 0.01139 |
| MCF7 | P22077 | 9.992797406 | 0.6061 | 0.38623 |
| MCF7 | P22077 | 31.6 | -0.3409 | 0.56463 |
| MCF7 | P22077 | 50.0 | -0.2924 | 0.23703 |
| MCF7 | PB49673382 | 0.009992797 | 1.0534 | -0.00211 |
| MCF7 | PB49673382 | 0.0316 | 0.9780 | -0.00090 |
| MCF7 | PB49673382 | 0.099927974 | 1.0003 | -0.00140 |
| MCF7 | PB49673382 | 0.316 | 0.9813 | 0.00101 |
| MCF7 | PB49673382 | 0.999279741 | 1.0023 | 0.00045 |
| MCF7 | PB49673382 | 3.16 | 0.7872 | 0.00416 |
| MCF7 | PB49673382 | 9.992797406 | 0.1982 | 0.07278 |