Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| Hs 578T | USP7-IN-1 | 0.099927974 | 1.0383 | -0.01027 |
| Hs 578T | USP7-IN-1 | 0.316 | 1.0632 | 0.00206 |
| Hs 578T | USP7-IN-1 | 0.999279741 | 0.8618 | 0.06256 |
| Hs 578T | USP7-IN-1 | 3.16 | 1.0236 | 0.00305 |
| Hs 578T | USP7-IN-1 | 9.992797406 | 1.0104 | 0.00174 |
| Hs 578T | USP7-IN-1 | 31.6 | 0.9287 | 0.00423 |
| Hs 578T | USP7-IN-1 | 50.0 | 0.8486 | -0.00056 |
| Hs 578T | Doxycycline | 0.009992797 | 0.6758 | 0.06865 |
| Hs 578T | Doxycycline | 0.0316 | 0.9980 | -0.00855 |
| Hs 578T | Doxycycline | 0.099927974 | 0.9967 | 0.00483 |
| Hs 578T | Doxycycline | 0.316 | 0.9640 | -0.01261 |
| Hs 578T | Doxycycline | 0.999279741 | 1.0184 | -0.00400 |
| Hs 578T | Doxycycline | 3.16 | 0.9412 | -0.00953 |
| Hs 578T | Doxycycline | 9.992797406 | 1.0952 | -0.00238 |
| Hs 578T | Doxycycline | 31.6 | 1.3436 | 0.03855 |
| Hs 578T | Doxycycline | 50.0 | 1.3637 | -0.02647 |
| Hs 578T | GW7647 | 0.009992797 | 1.0947 | -0.00685 |
| Hs 578T | GW7647 | 0.0316 | 1.1603 | -0.00350 |
| Hs 578T | GW7647 | 0.099927974 | 0.9515 | 0.00601 |
| Hs 578T | GW7647 | 0.316 | 0.9332 | 0.00800 |
| Hs 578T | GW7647 | 0.999279741 | 1.0295 | -0.00780 |
| Hs 578T | GW7647 | 3.16 | 1.0737 | -0.00860 |
| Hs 578T | GW7647 | 9.992797406 | 1.0132 | -0.00527 |
| Hs 578T | GW7647 | 31.6 | 1.0271 | 0.00782 |
| Hs 578T | GW7647 | 50.0 | 0.8977 | 0.02416 |