Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC202 | z-VAE(OMe)-fmk | 0.999279741 | 0.9189 | 0.00824 |
| HCC202 | z-VAE(OMe)-fmk | 3.16 | 0.9745 | 0.01126 |
| HCC202 | z-VAE(OMe)-fmk | 9.992797406 | 0.8848 | -0.00550 |
| HCC202 | z-VAE(OMe)-fmk | 31.6 | 1.0085 | 0.00501 |
| HCC202 | z-VAE(OMe)-fmk | 50.0 | 1.0943 | -0.01716 |
| Hs 578T | 1247825-37-1 | 0.009992797 | 1.0070 | -0.00434 |
| Hs 578T | 1247825-37-1 | 0.0316 | 0.9407 | 0.01512 |
| Hs 578T | 1247825-37-1 | 0.099927974 | 1.0487 | -0.00062 |
| Hs 578T | 1247825-37-1 | 0.316 | 1.0434 | -0.00342 |
| Hs 578T | 1247825-37-1 | 0.999279741 | 0.9724 | 0.00170 |
| Hs 578T | 1247825-37-1 | 3.16 | 0.8457 | 0.00393 |
| Hs 578T | 1247825-37-1 | 9.992797406 | 0.6292 | 0.02921 |
| Hs 578T | 1247825-37-1 | 31.6 | -0.3555 | 0.57240 |
| Hs 578T | 1247825-37-1 | 50.0 | -0.2177 | 0.51404 |
| Hs 578T | b-AP15 | 0.009992797 | 0.9986 | 0.00572 |
| Hs 578T | b-AP15 | 0.0316 | 0.9704 | -0.00603 |
| Hs 578T | b-AP15 | 0.099927974 | 0.3858 | 0.17833 |
| Hs 578T | b-AP15 | 0.316 | -0.4451 | 0.68857 |
| Hs 578T | b-AP15 | 0.999279741 | -0.2928 | 0.48932 |
| Hs 578T | b-AP15 | 3.16 | -0.3132 | 0.37302 |
| Hs 578T | b-AP15 | 9.992797406 | -0.5094 | 0.75201 |
| Hs 578T | b-AP15 | 31.6 | -0.5434 | 0.77480 |
| Hs 578T | b-AP15 | 50.0 | -0.5357 | 0.75000 |
| Hs 578T | USP7-IN-1 | 0.009992797 | 1.0304 | 0.00620 |
| Hs 578T | USP7-IN-1 | 0.0316 | 1.0637 | -0.01056 |