Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC202 | Mitoxantrone | 31.6 | -0.6992 | 0.41629 |
| HCC202 | Mitoxantrone | 50.0 | -0.7112 | 0.20665 |
| HCC202 | ML-323 | 0.009992797 | 1.0671 | -0.00368 |
| HCC202 | ML-323 | 0.0316 | 0.9632 | 0.01225 |
| HCC202 | ML-323 | 0.099927974 | 0.9945 | 0.00361 |
| HCC202 | ML-323 | 0.316 | 1.1033 | 0.01027 |
| HCC202 | ML-323 | 0.999279741 | 0.8379 | 0.01296 |
| HCC202 | ML-323 | 3.16 | 0.7048 | 0.02694 |
| HCC202 | ML-323 | 9.992797406 | 0.8374 | -0.00243 |
| HCC202 | ML-323 | 31.6 | 0.7324 | 0.01023 |
| HCC202 | ML-323 | 50.0 | 0.5409 | 0.01118 |
| HCC202 | Pevonedistat | 0.009992797 | 1.0099 | 0.01853 |
| HCC202 | Pevonedistat | 0.0316 | 0.8561 | 0.01609 |
| HCC202 | Pevonedistat | 0.099927974 | 0.8448 | 0.03102 |
| HCC202 | Pevonedistat | 0.316 | 0.2922 | 0.09513 |
| HCC202 | Pevonedistat | 0.999279741 | 0.1647 | 0.07923 |
| HCC202 | Pevonedistat | 3.16 | -0.0492 | 0.09146 |
| HCC202 | Pevonedistat | 9.992797406 | -0.0188 | 0.12967 |
| HCC202 | Pevonedistat | 31.6 | -0.0886 | 0.15194 |
| HCC202 | Pevonedistat | 50.0 | -0.1206 | 0.10607 |
| HCC202 | P22077 | 0.009992797 | 0.8161 | -0.00045 |
| HCC202 | P22077 | 0.0316 | 1.1421 | 0.00265 |
| HCC202 | P22077 | 0.099927974 | 0.9675 | 0.00679 |
| HCC202 | P22077 | 0.316 | 0.9001 | -0.01582 |
| HCC202 | P22077 | 0.999279741 | 0.9758 | 0.00492 |