Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC1954 Pimozide
0.009992797
 1.0020 -0.00409
HCC1954 Pimozide
0.0316
 1.0130 -0.00593
HCC1954 Pimozide
0.099927974
 0.9335 0.00034
HCC1954 Pimozide
0.316
 0.8583 0.00624
HCC1954 Pimozide
0.999279741
 1.0384 0.00356
HCC1954 Pimozide
3.16
 0.9185 0.01243
HCC1954 Pimozide
9.992797406
 0.5691 0.06014
HCC1954 Pimozide
31.6
 -0.3320 0.52164
HCC1954 Pimozide
50.0
 -0.3311 0.52850
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.8033 0.00624
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 1.0515 -0.02401
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.0279 0.00307
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 0.9616 0.01342
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.8955 0.00938
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.9680 0.01659
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.8824 0.01320
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.8537 0.02822
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.0243 0.01595
HCC1954 SB1-F-21
0.009992797
 1.0156 0.00282
HCC1954 SB1-F-21
0.0316
 1.0509 0.01469
HCC1954 SB1-F-21
0.099927974
 0.9914 -0.00371
HCC1954 SB1-F-21
0.316
 0.9079 0.11470
HCC1954 SB1-F-21
0.999279741
 -0.1346 0.43818
HCC1954 SB1-F-21
3.16
 -0.4177 0.62823
HCC1954 SB1-F-21
9.992797406
 -0.6189 0.65922