Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC202 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9434 -0.00142
HCC1500 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 1.0427 0.01003
HCC1500 HBX19818
9.992797406
 0.8113 0.03759
PDX1328 PB49673382
9.992797406
 0.4641 0.03883
HCC1954 Spautin-1
9.992797406
 0.3943 0.12237
PDX1258 HY-17541A
9.992797406
 0.2193 0.25091
HCC1419 LDN57444
9.992797406
 0.8758 0.06763
HCC1954 HBX19818
9.992797406
 0.8494 0.02130
HCC202 SB1-F-22
9.992797406
 0.8904 0.03008
HCC1954 1247825-37-1
9.992797406
 0.4655 0.06164
HCC1937 HBX 41108
9.992797406
 -0.0468 0.21613
BT-549 STK547622
9.992797406
 1.0067 -0.00058
HCC1806 HY-17541A
9.992797406
 0.7821 0.25020
HCC1937 HY-50736
9.992797406
 -0.5143 0.47915
Hs 578T Pevonedistat
9.992797406
 -0.0109 0.36826
PDX1258 P22077
9.992797406
 -0.3575 0.42380
HCC1954 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.8824 0.01320
MCF7 SJB2-043
9.992797406
 -0.2738 0.60939
HCC1500 Doxycycline
9.992797406
 0.8413 0.16728
HCC1419 SJB3-019A
9.992797406
 -0.6831 0.74373
MCF7 Spautin-1
9.992797406
 0.6330 0.02071
CAMA-1 ML-323
9.992797406
 0.7512 0.01767
MCF 10A GW7647
9.992797406
 0.9631 0.00485