Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1419 | ML-323 | 0.0316 | 1.0372 | -0.00612 |
| HCC1419 | ML-323 | 0.099927974 | 0.9037 | 0.00217 |
| HCC1419 | ML-323 | 0.316 | 1.0033 | -0.00239 |
| HCC1419 | ML-323 | 0.999279741 | 0.9832 | -0.00142 |
| HCC1419 | ML-323 | 3.16 | 0.8121 | 0.00193 |
| HCC1419 | ML-323 | 9.992797406 | 0.8354 | -0.00744 |
| HCC1419 | ML-323 | 31.6 | 0.2206 | 0.00858 |
| HCC1419 | ML-323 | 50.0 | 0.0958 | 0.01219 |
| HCC1419 | Pevonedistat | 0.009992797 | 0.8135 | -0.00040 |
| HCC1419 | Pevonedistat | 0.0316 | 1.1663 | 0.00216 |
| HCC1419 | Pevonedistat | 0.099927974 | 1.3392 | 0.01331 |
| HCC1419 | Pevonedistat | 0.316 | 0.8585 | 0.06896 |
| HCC1419 | Pevonedistat | 0.999279741 | 0.1905 | 0.16973 |
| HCC1419 | Pevonedistat | 3.16 | -0.0481 | 0.23034 |
| HCC1419 | Pevonedistat | 9.992797406 | -0.0934 | 0.26296 |
| HCC1419 | Pevonedistat | 31.6 | -0.0652 | 0.23936 |
| HCC1419 | Pevonedistat | 50.0 | -0.0244 | 0.17866 |
| HCC1419 | P22077 | 0.009992797 | 1.1352 | -0.00660 |
| HCC1419 | P22077 | 0.0316 | 1.0100 | -0.00858 |
| HCC1419 | P22077 | 0.099927974 | 1.1329 | -0.00102 |
| HCC1419 | P22077 | 0.316 | 1.1086 | -0.00932 |
| HCC1419 | P22077 | 0.999279741 | 1.0463 | -0.00307 |
| HCC1419 | P22077 | 3.16 | 0.9378 | 0.04609 |
| HCC1419 | P22077 | 9.992797406 | 0.3461 | 0.48401 |
| HCC1419 | P22077 | 31.6 | -0.6640 | 0.70918 |