Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC1419 P22077
50.0
 -0.6824 0.26168
HCC1419 PB49673382
0.009992797
 0.9651 -0.00388
HCC1419 PB49673382
0.0316
 1.0032 -0.00400
HCC1419 PB49673382
0.099927974
 1.0810 -0.00519
HCC1419 PB49673382
0.316
 1.0011 -0.00043
HCC1419 PB49673382
0.999279741
 0.9552 -0.00518
HCC1419 PB49673382
3.16
 0.8745 -0.00460
HCC1419 PB49673382
9.992797406
 0.1489 0.01161
HCC1419 PB49673382
31.6
 0.0084 0.03955
HCC1419 PB49673382
50.0
 0.0152 0.04096
HCC1419 Pimozide
0.009992797
 0.9649 -0.00411
HCC1419 Pimozide
0.0316
 1.0370 -0.00846
HCC1419 Pimozide
0.099927974
 1.0567 0.00037
HCC1419 Pimozide
0.316
 0.8415 -0.00161
HCC1419 Pimozide
0.999279741
 0.9352 0.00546
HCC1419 Pimozide
3.16
 0.6789 0.00494
HCC1419 Pimozide
9.992797406
 0.2981 0.07046
HCC1419 Pimozide
31.6
 -0.6535 0.71098
HCC1419 Pimozide
50.0
 -0.7003 0.70234
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9305 -0.00607
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.8769 0.00151
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 0.9675 0.00763
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.1377 0.00309
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 1.0040 -0.00221
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 1.0657 -0.00605