Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
CAMA-1 Pimozide
0.316
 0.7827 0.00729
CAMA-1 Pimozide
0.999279741
 0.9624 -0.00263
CAMA-1 Pimozide
3.16
 0.7789 0.02702
CAMA-1 Pimozide
9.992797406
 0.5921 0.05805
CAMA-1 Pimozide
31.6
 -0.6260 0.62447
CAMA-1 Pimozide
50.0
 -0.5624 0.57465
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.8183 0.00746
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.9994 0.00617
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.0365 0.00428
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.0373 0.00715
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9320 -0.00006
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.9715 0.01011
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.8594 0.00343
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9558 0.01059
CAMA-1 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 0.9375 0.01246
CAMA-1 SB1-F-21
0.009992797
 0.9497 -0.00047
CAMA-1 SB1-F-21
0.0316
 1.0467 0.00830
CAMA-1 SB1-F-21
0.099927974
 0.7983 0.03583
CAMA-1 SB1-F-21
0.316
 0.6040 0.07760
CAMA-1 SB1-F-21
0.999279741
 -0.0349 0.20622
CAMA-1 SB1-F-21
3.16
 -0.2599 0.45748
CAMA-1 SB1-F-21
9.992797406
 -0.4935 0.61462
CAMA-1 SB1-F-21
31.6
 -0.6374 0.71254
CAMA-1 SB1-F-21
50.0
 -0.6495 0.45937
CAMA-1 SB1-F-22
0.009992797
 1.0987 -0.00791