Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1258 | ML-323 | 31.6 | 0.7683 | 0.01252 |
| PDX1258 | ML-323 | 50.0 | 0.9266 | -0.00130 |
| PDX1258 | Pevonedistat | 0.009992797 | 0.9819 | 0.00434 |
| PDX1258 | Pevonedistat | 0.0316 | 0.9436 | 0.02179 |
| PDX1258 | Pevonedistat | 0.099927974 | 0.6911 | 0.04346 |
| PDX1258 | Pevonedistat | 0.316 | 0.4948 | 0.10718 |
| PDX1258 | Pevonedistat | 0.999279741 | 0.0746 | 0.21096 |
| PDX1258 | Pevonedistat | 3.16 | -0.1046 | 0.28636 |
| PDX1258 | Pevonedistat | 9.992797406 | -0.2005 | 0.37187 |
| PDX1258 | Pevonedistat | 31.6 | -0.2816 | 0.40161 |
| PDX1258 | Pevonedistat | 50.0 | -0.3092 | 0.26367 |
| PDX1258 | P22077 | 0.009992797 | 1.0122 | 0.00525 |
| PDX1258 | P22077 | 0.0316 | 1.0094 | 0.00090 |
| PDX1258 | P22077 | 0.099927974 | 0.9355 | -0.00249 |
| PDX1258 | P22077 | 0.316 | 1.0422 | NaN |
| PDX1258 | P22077 | 0.999279741 | 0.9235 | -0.01038 |
| PDX1258 | P22077 | 3.16 | 0.5143 | 0.09081 |
| PDX1258 | P22077 | 9.992797406 | -0.3575 | 0.42380 |
| PDX1258 | P22077 | 31.6 | -0.5772 | 0.59766 |
| PDX1258 | P22077 | 50.0 | -0.5698 | 0.57507 |
| PDX1258 | PB49673382 | 0.009992797 | 0.9654 | 0.01115 |
| PDX1258 | PB49673382 | 0.0316 | 0.9135 | -0.00166 |
| PDX1258 | PB49673382 | 0.099927974 | 0.9920 | 0.00488 |
| PDX1258 | PB49673382 | 0.316 | 0.9221 | -0.00058 |
| PDX1258 | PB49673382 | 0.999279741 | 1.0057 | -0.01419 |