Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1258 | MI-2 | 0.009992797 | 1.0464 | 0.00330 |
| PDX1258 | MI-2 | 0.0316 | 0.9581 | 0.00107 |
| PDX1258 | MI-2 | 0.099927974 | 0.9920 | 0.00232 |
| PDX1258 | MI-2 | 0.316 | 0.9173 | 0.01984 |
| PDX1258 | MI-2 | 0.999279741 | 0.6767 | 0.08806 |
| PDX1258 | MI-2 | 3.16 | 0.3493 | 0.32044 |
| PDX1258 | MI-2 | 9.992797406 | -0.5602 | 0.59177 |
| PDX1258 | MI-2 | 31.6 | -0.6053 | 0.60036 |
| PDX1258 | MI-2 | 50.0 | -0.5808 | 0.19288 |
| PDX1258 | Mitoxantrone | 0.009992797 | 0.4192 | 0.14178 |
| PDX1258 | Mitoxantrone | 0.0316 | 0.2279 | 0.23127 |
| PDX1258 | Mitoxantrone | 0.099927974 | 0.1681 | 0.25055 |
| PDX1258 | Mitoxantrone | 0.316 | 0.0435 | 0.27948 |
| PDX1258 | Mitoxantrone | 0.999279741 | -0.1324 | 0.35119 |
| PDX1258 | Mitoxantrone | 3.16 | -0.5207 | 0.63617 |
| PDX1258 | Mitoxantrone | 9.992797406 | -0.6058 | 0.65769 |
| PDX1258 | Mitoxantrone | 31.6 | -0.6687 | 0.67689 |
| PDX1258 | Mitoxantrone | 50.0 | -0.6933 | 0.69281 |
| PDX1258 | ML-323 | 0.009992797 | 1.0385 | 0.00351 |
| PDX1258 | ML-323 | 0.0316 | 1.0755 | -0.00911 |
| PDX1258 | ML-323 | 0.099927974 | 1.0400 | -0.00472 |
| PDX1258 | ML-323 | 0.316 | 1.0337 | 0.00364 |
| PDX1258 | ML-323 | 0.999279741 | 0.9318 | -0.00155 |
| PDX1258 | ML-323 | 3.16 | 0.9187 | 0.02615 |
| PDX1258 | ML-323 | 9.992797406 | 0.9613 | -0.02325 |