Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset - HMS LINCS Database

Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

Filter results: >>>>

Cell	Small Molecule	Primary Target	Pathway	GR50	GRmax	GR_AOC	Death_AUC	GR Hill Coefficient	GEC50	GR r2
BT-549	Luminespib	HSP90	Misc	0.0053858	-0.1064	0.6123	0.1201	5.0000	0.0055748	0.99911
BT-549	Cabozantinib	VEGFR2/MET	RTK	10.1855	0.5329	0.0124	0.0096	5.0000	12.5665	0.95054
MCF 10A	Dinaciclib	pan CDK	Cell cycle	0.016244	-0.2300	0.5279	0.2344	5.0000	0.017523	0.99904
T47D	A-1210477	Mcl-1	Misc	Inf	0.5752	0.0227	0.0055	5.0000	3.7781	0.96287
HCC38	Luminespib	HSP90	Misc	0.0071367	-0.2087	0.6295	0.1926	5.0000	0.0076296	0.99771
HCC1419	TGX221	PI3Kb	PI3K/mTOR	Inf	0.7941	-0.0049	0.0002	5.0000	3.889	0.79312
T47D	Dinaciclib	pan CDK	Cell cycle	0.019853	-0.2109	0.4815	0.0484	5.0000	0.021113	0.99494
HCC70	Dinaciclib	pan CDK	Cell cycle	0.01286	-0.9093	0.8338	0.3254	5.0000	0.015807	0.9991
HCC70	Luminespib	HSP90	Misc	0.007646	-0.5826	0.7792	0.2409	5.0000	0.0088695	0.99752
HCC70	Ceritinib	ALK	RTK	3.1923	-0.8808	0.1379	0.0703	5.0000	3.9213	0.99483
PDX1258	Luminespib	HSP90	Misc	0.01007	-0.2899	0.6101	0.1943	5.0000	0.011049	0.99799
HCC1954	Cabozantinib	VEGFR2/MET	RTK	10.9106	0.6390	-0.0135	-0.0074	5.0000	13.0234	0.87916
PDXHCI002	TGX221	PI3Kb	PI3K/mTOR	Inf	0.8545	-0.0204	-0.0045	5.0000	4.5889	0.61889
SUM159PT	Dinaciclib	pan CDK	Cell cycle	0.016967	-0.0646	0.4536	0.1030	5.0000	0.017277	0.99948
PDX1328	Olaparib	PARP	Misc	Inf	0.7634	0.0268	-0.0025	5.0000	1.7254	0.86133