Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset - HMS LINCS Database

Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

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Cell	Small Molecule	Primary Target	Pathway	GR50	GRmax	GR_AOC	Death_AUC	GR Hill Coefficient	GEC50	GR r2
Hs 578T	Volasertib	PLK	Cell cycle	0.0025675	-0.3123	0.8198	0.3337	3.0081	0.0029864	0.9987
SUM159PT	Abemaciclib	CDK4/6	Cell cycle	0.28398	-0.4677	0.4585	0.1015	0.4799	2.802	0.95259
SUM159PT	Palbociclib	CDK4/6	Cell cycle	1.1058	0.3876	0.1990	-0.0006	0.6326	0.40763	0.99661
SUM159PT	AZD7762	CHK1/2	Cell cycle	0.81589	-0.1124	0.2697	0.0926	1.5031	0.93462	0.99443
SUM159PT	Volasertib	PLK	Cell cycle	0.024832	0.0468	0.3873	0.1208	3.5660	0.024055	0.99966
MDA-MB-134-VI	Palbociclib	CDK4/6	Cell cycle	0.0092186	0.1787	0.5339	-0.0169	1.7301	0.0071324	0.98727
MDA-MB-134-VI	AZD7762	CHK1/2	Cell cycle	0.10625	-0.6459	0.6552	0.1488	1.1125	0.22232	0.99438
MDA-MB-134-VI	Volasertib	PLK	Cell cycle	0.0027209	-0.6274	1.0260	0.2671	5.0000	0.0032225	0.99553
MDA-MB-361	AZD7762	CHK1/2	Cell cycle	0.0076402	-0.6753	1.0533	0.2116	2.0458	0.010426	0.97675
MDA-MB-361	Volasertib	PLK	Cell cycle	0.0035439	-0.4972	0.8204	0.1921	4.6311	0.0040451	0.98886
MDA-MB-453	Dinaciclib	pan CDK	Cell cycle	0.011359	-0.2569	0.5807	0.1358	3.4728	0.012824	0.99835
CAL-51	Dinaciclib	pan CDK	Cell cycle	0.014709	-0.3585	0.5985	0.2374	3.5319	0.017105	0.99939
CAL-51	Volasertib	PLK	Cell cycle	0.0059136	-0.3372	0.6787	0.2411	3.0715	0.0068268	0.99697
BT-20	Dinaciclib	pan CDK	Cell cycle	0.018482	-0.6979	0.6791	0.3193	3.4864	0.02362	0.99822
BT-20	Volasertib	PLK	Cell cycle	0.0056337	-0.5339	0.7904	0.3461	2.3226	0.0076094	0.99851