Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
Hs 578T Vorinostat
0.001
HDAC
Misc
 1.0117 0.00084
HCC1806 Vorinostat
0.0031623
HDAC
Misc
 1.0396 -0.00386
MCF 10A Vorinostat
0.0031623
HDAC
Misc
 0.9971 0.00002
HCC1806 Vorinostat
0.001
HDAC
Misc
 1.0136 -0.00693
MDA-MB-231 Vorinostat
10.0
HDAC
Misc
 -0.3848 0.58110
Hs 578T Vorinostat
0.031623
HDAC
Misc
 1.0296 0.00131
Hs 578T Vorinostat
0.31623
HDAC
Misc
 0.9301 0.00606
MCF 10A Vorinostat
0.1
HDAC
Misc
 0.9822 0.00019
MCF 10A Vorinostat
0.31623
HDAC
Misc
 0.9417 -0.00164
Hs 578T Vorinostat
0.1
HDAC
Misc
 1.0643 -0.00098
HCC1806 Vorinostat
0.031623
HDAC
Misc
 1.0082 -0.00167
HCC1806 Vorinostat
0.1
HDAC
Misc
 0.9246 0.00705
HCC1806 Vorinostat
10.0
HDAC
Misc
 0.0178 0.19873
HCC1806 Vorinostat
3.1623
HDAC
Misc
 0.1581 0.17812
Hs 578T Vorinostat
1.0
HDAC
Misc
 0.4258 0.10793
Hs 578T Vorinostat
3.1623
HDAC
Misc
 -0.0561 0.35835
MCF7 Vorinostat
0.031623
HDAC
Misc
 0.9936 0.00264
Hs 578T Vorinostat
0.01
HDAC
Misc
 1.0665 -0.00223
HCC1806 Vorinostat
1.0
HDAC
Misc
 0.5599 0.05417
HCC1806 Vorinostat
0.31623
HDAC
Misc
 0.8452 0.01588
MCF7 Vorinostat
3.1623
HDAC
Misc
 -0.0037 0.26078
Hs 578T Vorinostat
0.0031623
HDAC
Misc
 0.9668 -0.00319
MCF 10A Vorinostat
0.001
HDAC
Misc
 1.0052 0.00132
SK-BR-3 Vorinostat
0.1
HDAC
Misc
 1.1297 -0.00228
SK-BR-3 Vorinostat
0.031623
HDAC
Misc
 1.1091 0.00223