Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-549 Doxorubicin
0.031623
Chemo
Chemotherapy
 -0.0243 0.24440
BT-549 Doxorubicin
0.1
Chemo
Chemotherapy
 -0.0922 0.20044
BT-549 Doxorubicin
0.31623
Chemo
Chemotherapy
 -0.1163 0.22181
BT-549 Doxorubicin
1.0
Chemo
Chemotherapy
 -0.1853 0.31788
BT-549 Doxorubicin
3.1623
Chemo
Chemotherapy
 -0.3312 0.45632
BT-549 Taxol
0.0001
Chemo
Chemotherapy
 1.0080 0.01654
BT-549 Taxol
0.00031623
Chemo
Chemotherapy
 1.0248 0.00400
BT-549 Taxol
0.001
Chemo
Chemotherapy
 0.9713 0.02904
BT-549 Taxol
0.0031623
Chemo
Chemotherapy
 0.3527 0.25585
BT-549 Taxol
0.01
Chemo
Chemotherapy
 0.0552 0.35991
BT-549 Taxol
0.031623
Chemo
Chemotherapy
 -0.0726 0.33023
BT-549 Taxol
0.1
Chemo
Chemotherapy
 -0.1583 0.35231
BT-549 Taxol
0.31623
Chemo
Chemotherapy
 -0.1643 0.34489
BT-549 Taxol
1.0
Chemo
Chemotherapy
 -0.2074 0.38064
BT-549 Topotecan
0.0010833
Topo I
Chemotherapy
 0.9604 0.00435
BT-549 Topotecan
0.0033333
Topo I
Chemotherapy
 0.8725 0.02903
BT-549 Topotecan
0.01
Topo I
Chemotherapy
 0.3809 0.21149
BT-549 Topotecan
0.031667
Topo I
Chemotherapy
 0.0383 0.24369
BT-549 Topotecan
0.1
Topo I
Chemotherapy
 -0.0091 0.26037
BT-549 Topotecan
0.31623
Topo I
Chemotherapy
 -0.0640 0.26130
BT-549 Topotecan
1.0
Topo I
Chemotherapy
 -0.1475 0.33549
BT-549 Topotecan
3.1623
Topo I
Chemotherapy
 -0.1977 0.35547
BT-549 Topotecan
10.0
Topo I
Chemotherapy
 -0.2410 0.34056
BT-549 Etoposide
0.0010833
Topo II
Chemotherapy
 0.9796 0.00633
BT-549 Etoposide
0.0033333
Topo II
Chemotherapy
 1.0136 0.00089