Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
SUM159PT | Cisplatin | 0.0033333 | Chemo | Chemotherapy | 0.9899 | 0.01848 |
SUM159PT | Cisplatin | 0.01 | Chemo | Chemotherapy | 0.9813 | 0.02194 |
SUM159PT | Cisplatin | 0.031667 | Chemo | Chemotherapy | 1.0002 | 0.00417 |
SUM159PT | Cisplatin | 0.1 | Chemo | Chemotherapy | 0.9843 | 0.00949 |
SUM159PT | Cisplatin | 0.31623 | Chemo | Chemotherapy | 0.9506 | 0.00299 |
SUM159PT | Cisplatin | 1.0 | Chemo | Chemotherapy | 0.8889 | -0.00321 |
SUM159PT | Cisplatin | 3.1623 | Chemo | Chemotherapy | 0.7038 | 0.01423 |
SUM159PT | Cisplatin | 10.0 | Chemo | Chemotherapy | 0.1742 | 0.28570 |
SUM159PT | Doxorubicin | 0.00031623 | Chemo | Chemotherapy | 0.9937 | 0.00098 |
SUM159PT | Doxorubicin | 0.001 | Chemo | Chemotherapy | 0.9902 | 0.00264 |
SUM159PT | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.9609 | 0.00146 |
SUM159PT | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.7792 | 0.04792 |
SUM159PT | Doxorubicin | 0.031623 | Chemo | Chemotherapy | 0.2353 | 0.36106 |
SUM159PT | Doxorubicin | 0.1 | Chemo | Chemotherapy | -0.0130 | 0.51767 |
SUM159PT | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.0490 | 0.46703 |
SUM159PT | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.1180 | 0.50382 |
SUM159PT | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.2740 | 0.76625 |
SUM159PT | Taxol | 0.0001 | Chemo | Chemotherapy | 1.0008 | 0.00231 |
SUM159PT | Taxol | 0.00031623 | Chemo | Chemotherapy | 0.9987 | -0.00197 |
SUM159PT | Taxol | 0.001 | Chemo | Chemotherapy | 1.0079 | 0.01346 |
SUM159PT | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.7176 | 0.11136 |
SUM159PT | Taxol | 0.01 | Chemo | Chemotherapy | 0.0915 | 0.40074 |
SUM159PT | Taxol | 0.031623 | Chemo | Chemotherapy | -0.0854 | 0.50239 |
SUM159PT | Taxol | 0.1 | Chemo | Chemotherapy | -0.1229 | 0.55032 |
SUM159PT | Taxol | 0.31623 | Chemo | Chemotherapy | -0.1485 | 0.57465 |