Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SUM1315MO2 Vorinostat
0.0031623
HDAC
Misc
 1.0478 0.00409
SUM1315MO2 Vorinostat
0.01
HDAC
Misc
 1.0875 0.00474
SUM1315MO2 Vorinostat
0.031623
HDAC
Misc
 1.0215 0.00515
SUM1315MO2 Vorinostat
0.1
HDAC
Misc
 0.9901 0.00926
SUM1315MO2 Vorinostat
0.31623
HDAC
Misc
 1.0532 0.01611
SUM1315MO2 Vorinostat
1.0
HDAC
Misc
 0.8295 0.07806
SUM1315MO2 Vorinostat
3.1623
HDAC
Misc
 0.1264 0.27563
SUM1315MO2 Vorinostat
10.0
HDAC
Misc
 -0.0668 0.20050
SUM1315MO2 Luminespib
0.0001
HSP90
Misc
 1.0309 0.00183
SUM1315MO2 Luminespib
0.00031623
HSP90
Misc
 1.0911 0.00111
SUM1315MO2 Luminespib
0.001
HSP90
Misc
 1.0272 -0.00281
SUM1315MO2 Luminespib
0.0031623
HSP90
Misc
 0.9116 0.03300
SUM1315MO2 Luminespib
0.01
HSP90
Misc
 -0.0836 0.23209
SUM1315MO2 Luminespib
0.031623
HSP90
Misc
 -0.1236 0.26285
SUM1315MO2 Luminespib
0.1
HSP90
Misc
 -0.0690 0.24463
SUM1315MO2 Luminespib
0.31623
HSP90
Misc
 -0.0810 0.23930
SUM1315MO2 Luminespib
1.0
HSP90
Misc
 -0.0735 0.22453
SUM1315MO2 A-1210477
0.001
Mcl-1
Misc
 1.1069 -0.00275
SUM1315MO2 A-1210477
0.0031623
Mcl-1
Misc
 1.0655 0.00031
SUM1315MO2 A-1210477
0.01
Mcl-1
Misc
 1.0894 0.00296
SUM1315MO2 A-1210477
0.031623
Mcl-1
Misc
 1.0759 0.00211
SUM1315MO2 A-1210477
0.1
Mcl-1
Misc
 1.0708 -0.00859
SUM1315MO2 A-1210477
0.31623
Mcl-1
Misc
 1.0897 -0.00853
SUM1315MO2 A-1210477
1.0
Mcl-1
Misc
 1.1179 -0.01427
SUM1315MO2 A-1210477
3.1623
Mcl-1
Misc
 0.9925 -0.00574