Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1143 Taxol
0.1
Chemo
Chemotherapy
 -0.2735 0.46739
HCC1143 Taxol
0.31623
Chemo
Chemotherapy
 -0.2774 0.50922
HCC1143 Taxol
1.0
Chemo
Chemotherapy
 -0.3349 0.51837
HCC1143 Topotecan
0.0010833
Topo I
Chemotherapy
 0.9943 0.00386
HCC1143 Topotecan
0.0033333
Topo I
Chemotherapy
 0.8863 0.02171
HCC1143 Topotecan
0.01
Topo I
Chemotherapy
 0.4372 0.12951
HCC1143 Topotecan
0.031667
Topo I
Chemotherapy
 -0.0455 0.29237
HCC1143 Topotecan
0.1
Topo I
Chemotherapy
 0.0011 0.38008
HCC1143 Topotecan
0.31623
Topo I
Chemotherapy
 -0.1114 0.38022
HCC1143 Topotecan
1.0
Topo I
Chemotherapy
 -0.2161 0.39434
HCC1143 Topotecan
3.1623
Topo I
Chemotherapy
 -0.4200 0.54915
HCC1143 Topotecan
10.0
Topo I
Chemotherapy
 -0.4304 0.55051
HCC1143 Etoposide
0.0010833
Topo II
Chemotherapy
 0.9894 -0.00205
HCC1143 Etoposide
0.0033333
Topo II
Chemotherapy
 0.9660 0.00066
HCC1143 Etoposide
0.01
Topo II
Chemotherapy
 1.0336 0.00314
HCC1143 Etoposide
0.031667
Topo II
Chemotherapy
 0.9976 0.00505
HCC1143 Etoposide
0.1
Topo II
Chemotherapy
 0.9082 0.02175
HCC1143 Etoposide
0.31623
Topo II
Chemotherapy
 0.6974 0.06130
HCC1143 Etoposide
1.0
Topo II
Chemotherapy
 0.1083 0.24661
HCC1143 Etoposide
3.1623
Topo II
Chemotherapy
 -0.1661 0.38534
HCC1143 Etoposide
10.0
Topo II
Chemotherapy
 -0.1664 0.42909
HCC1143 Dasatinib
0.001
BCR/ABL
MAPK/nRTK
 0.8656 0.01140
HCC1143 Dasatinib
0.0031623
BCR/ABL
MAPK/nRTK
 0.7877 0.02054
HCC1143 Dasatinib
0.01
BCR/ABL
MAPK/nRTK
 0.8135 0.03776
HCC1143 Dasatinib
0.031623
BCR/ABL
MAPK/nRTK
 0.7023 0.06141