Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MCF 10A Luminespib
0.0031623
HSP90
Misc
 0.9428 -0.00143
MCF 10A Luminespib
0.01
HSP90
Misc
 0.2559 0.20941
MCF 10A Luminespib
0.031623
HSP90
Misc
 -0.1709 0.54579
MCF 10A Luminespib
0.1
HSP90
Misc
 -0.1730 0.54230
MCF 10A Luminespib
0.31623
HSP90
Misc
 -0.1717 0.53790
MCF 10A Luminespib
1.0
HSP90
Misc
 -0.1680 0.52779
MCF 10A A-1210477
0.001
Mcl-1
Misc
 0.9990 -0.00061
MCF 10A A-1210477
0.0031623
Mcl-1
Misc
 1.0050 0.00067
MCF 10A A-1210477
0.01
Mcl-1
Misc
 1.0049 0.00097
MCF 10A A-1210477
0.031623
Mcl-1
Misc
 1.0045 0.00073
MCF 10A A-1210477
0.1
Mcl-1
Misc
 0.9996 0.00015
MCF 10A A-1210477
0.31623
Mcl-1
Misc
 1.0036 -0.00030
MCF 10A A-1210477
1.0
Mcl-1
Misc
 1.0068 -0.00085
MCF 10A A-1210477
3.1623
Mcl-1
Misc
 0.9858 0.00085
MCF 10A A-1210477
10.0
Mcl-1
Misc
 0.9527 0.00341
MCF 10A Olaparib
0.001
PARP
Misc
 1.0020 0.00124
MCF 10A Olaparib
0.0031623
PARP
Misc
 0.9976 -0.00060
MCF 10A Olaparib
0.01
PARP
Misc
 0.9959 -0.00028
MCF 10A Olaparib
0.031623
PARP
Misc
 0.9772 -0.00149
MCF 10A Olaparib
0.1
PARP
Misc
 0.9780 -0.00061
MCF 10A Olaparib
0.31623
PARP
Misc
 0.9687 -0.00058
MCF 10A Olaparib
1.0
PARP
Misc
 0.9489 -0.00263
MCF 10A Olaparib
3.1623
PARP
Misc
 0.9093 -0.00059
MCF 10A Olaparib
10.0
PARP
Misc
 0.7945 -0.00093
MCF 10A Bleomycin
0.0010833
Radiation
Misc
 0.9810 -0.00464