Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
HCC1395 | A-1210477 | 3.1623 | Mcl-1 | Misc | 1.0636 | -0.00924 |
MCF 10A | A-1210477 | 0.0031623 | Mcl-1 | Misc | 1.0050 | 0.00067 |
MCF 10A | A-1210477 | 0.001 | Mcl-1 | Misc | 0.9990 | -0.00061 |
MDA-MB-231 | A-1210477 | 0.001 | Mcl-1 | Misc | 0.9554 | -0.00434 |
HCC1419 | A-1210477 | 0.01 | Mcl-1 | Misc | 0.9714 | -0.00232 |
HCC1419 | A-1210477 | 0.031623 | Mcl-1 | Misc | 0.9650 | 0.00392 |
BT-549 | A-1210477 | 0.31623 | Mcl-1 | Misc | 0.9783 | 0.00059 |
MCF7 | A-1210477 | 0.001 | Mcl-1 | Misc | 0.9825 | -0.00133 |
BT-549 | A-1210477 | 0.0031623 | Mcl-1 | Misc | 1.0042 | 0.00177 |
BT-549 | A-1210477 | 0.001 | Mcl-1 | Misc | 0.9937 | -0.00156 |
BT-549 | A-1210477 | 0.01 | Mcl-1 | Misc | 0.9684 | 0.00918 |
BT-549 | A-1210477 | 0.1 | Mcl-1 | Misc | 0.9877 | 0.00665 |
MDA-MB-231 | A-1210477 | 1.0 | Mcl-1 | Misc | 0.9497 | 0.00062 |
BT-549 | A-1210477 | 0.031623 | Mcl-1 | Misc | 0.9914 | -0.00041 |
MCF 10A | A-1210477 | 0.31623 | Mcl-1 | Misc | 1.0036 | -0.00030 |
MCF 10A | A-1210477 | 0.1 | Mcl-1 | Misc | 0.9996 | 0.00015 |
MDA-MB-231 | A-1210477 | 0.31623 | Mcl-1 | Misc | 0.9833 | 0.00205 |
PDX1328 | A-1210477 | 0.01 | Mcl-1 | Misc | 0.9282 | 0.01137 |
MDA-MB-231 | A-1210477 | 0.1 | Mcl-1 | Misc | 0.9640 | 0.00781 |
Hs 578T | A-1210477 | 3.1623 | Mcl-1 | Misc | 1.0615 | 0.00422 |
MCF 10A | A-1210477 | 0.031623 | Mcl-1 | Misc | 1.0045 | 0.00073 |
Hs 578T | A-1210477 | 10.0 | Mcl-1 | Misc | 0.9419 | 0.00168 |
MCF 10A | A-1210477 | 3.1623 | Mcl-1 | Misc | 0.9858 | 0.00085 |
CAL-120 | A-1210477 | 10.0 | Mcl-1 | Misc | 0.9478 | 0.00530 |
CAL-120 | A-1210477 | 3.1623 | Mcl-1 | Misc | 0.9427 | 0.00506 |