Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| MCF 10A | A-1210477 | 1.0 | Mcl-1 | Misc | 1.0068 | -0.00085 |
| BT-20 | A-1210477 | 0.1 | Mcl-1 | Misc | 1.0869 | -0.00182 |
| HCC38 | A-1210477 | 0.31623 | Mcl-1 | Misc | 0.9662 | -0.00124 |
| HCC38 | A-1210477 | 0.031623 | Mcl-1 | Misc | 0.9783 | -0.00705 |
| MCF 10A | A-1210477 | 3.1623 | Mcl-1 | Misc | 0.9858 | 0.00085 |
| BT-20 | A-1210477 | 0.001 | Mcl-1 | Misc | 1.0130 | -0.01627 |
| BT-20 | A-1210477 | 0.031623 | Mcl-1 | Misc | 1.0678 | -0.00128 |
| MDA-MB-134-VI | A-1210477 | 0.01 | Mcl-1 | Misc | 1.0182 | 0.00906 |
| MDA-MB-134-VI | A-1210477 | 0.031623 | Mcl-1 | Misc | 1.1486 | -0.00249 |
| BT-20 | A-1210477 | 0.01 | Mcl-1 | Misc | 1.0461 | 0.00227 |
| MDA-MB-134-VI | A-1210477 | 0.1 | Mcl-1 | Misc | 1.0935 | 0.00150 |
| BT-20 | A-1210477 | 0.0031623 | Mcl-1 | Misc | 0.9994 | -0.00302 |
| MDA-MB-134-VI | A-1210477 | 0.31623 | Mcl-1 | Misc | 1.0596 | -0.00503 |
| BT-20 | A-1210477 | 0.31623 | Mcl-1 | Misc | 1.0544 | -0.00191 |
| BT-20 | A-1210477 | 10.0 | Mcl-1 | Misc | 0.8209 | 0.04589 |
| CAL-85-1 | A-1210477 | 3.1623 | Mcl-1 | Misc | 1.0227 | -0.00192 |
| MDA-MB-231 | A-1210477 | 0.01 | Mcl-1 | Misc | 0.8987 | 0.00765 |
| BT-20 | A-1210477 | 1.0 | Mcl-1 | Misc | 1.0474 | -0.00138 |
| BT-20 | A-1210477 | 3.1623 | Mcl-1 | Misc | 1.0977 | -0.01661 |
| HCC1143 | A-1210477 | 0.01 | Mcl-1 | Misc | 0.9545 | -0.00519 |
| HCC1143 | A-1210477 | 0.031623 | Mcl-1 | Misc | 0.9471 | -0.00290 |
| HCC38 | A-1210477 | 10.0 | Mcl-1 | Misc | 0.8870 | 0.00641 |
| MCF 10A | A-1210477 | 10.0 | Mcl-1 | Misc | 0.9527 | 0.00341 |
| PDXHCI002 | A-1210477 | 1.0 | Mcl-1 | Misc | 1.0639 | 0.00479 |
| PDXHCI002 | A-1210477 | 0.31623 | Mcl-1 | Misc | 1.0375 | 0.00572 |