Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MDA-MB-134-VI Ipatasertib
0.001
AKT
PI3K/mTOR
 1.2855 0.00701
BT-20 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9147 0.01166
MDA-MB-134-VI Ipatasertib
0.01
AKT
PI3K/mTOR
 1.2946 -0.00070
MDA-MB-134-VI Ipatasertib
0.31623
AKT
PI3K/mTOR
 1.1042 0.00674
MDA-MB-134-VI Ipatasertib
0.1
AKT
PI3K/mTOR
 1.0768 0.00558
BT-20 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9656 0.00133
BT-20 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.7880 0.01344
BT-20 Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9717 -0.00176
HCC38 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.7061 0.00156
CAL-85-1 Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0039 0.00417
CAL-85-1 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0529 0.00537
MDA-MB-134-VI Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4925 0.02851
CAL-85-1 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0046 -0.00801
MDA-MB-157 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0502 -0.00349
CAL-85-1 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4714 0.00336
BT-20 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.1015 0.23359
HCC1143 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9761 -0.00258
MDA-MB-157 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9336 0.01107
HCC1143 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9777 0.00590
BT-20 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.2981 0.08956
BT-20 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.4168 0.05632
MDA-MB-157 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9565 -0.00310
MDA-MB-157 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0214 0.00449
PDXHCI002 Ipatasertib
1.0
AKT
PI3K/mTOR
 1.1747 -0.02620
PDXHCI002 Ipatasertib
0.31623
AKT
PI3K/mTOR
 1.1369 -0.00729