Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| MCF7 | Ipatasertib | 0.31623 | AKT | PI3K/mTOR | 0.6830 | 0.02591 |
| SUM1315MO2 | Ipatasertib | 0.0031623 | AKT | PI3K/mTOR | 0.9968 | 0.00116 |
| MCF7 | Ipatasertib | 0.031623 | AKT | PI3K/mTOR | 0.9327 | 0.00677 |
| MCF7 | Ipatasertib | 0.001 | AKT | PI3K/mTOR | 0.9728 | 0.00441 |
| HCC1419 | Ipatasertib | 0.01 | AKT | PI3K/mTOR | 1.1535 | -0.00296 |
| HCC1419 | Ipatasertib | 0.0031623 | AKT | PI3K/mTOR | 1.0076 | 0.00354 |
| HCC1419 | Ipatasertib | 0.001 | AKT | PI3K/mTOR | 1.0159 | 0.00258 |
| HCC1419 | Ipatasertib | 0.31623 | AKT | PI3K/mTOR | 0.8917 | -0.00505 |
| HCC1419 | Ipatasertib | 0.1 | AKT | PI3K/mTOR | 1.0291 | 0.00075 |
| HCC1419 | Ipatasertib | 3.1623 | AKT | PI3K/mTOR | 0.6479 | 0.00467 |