Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

 Full screen view
Filter results: >>>>
Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
T47D Taselisib
0.31623
PI3Ka, g, d
PI3K/mTOR
 -0.0046 0.06924
T47D Taselisib
10.0
PI3Ka, g, d
PI3K/mTOR
 -0.1047 0.13876
T47D TGX221
0.001
PI3Kb
PI3K/mTOR
 1.0725 0.00126
T47D TGX221
0.01
PI3Kb
PI3K/mTOR
 1.0730 0.00055
T47D TGX221
0.031623
PI3Kb
PI3K/mTOR
 1.0945 -0.00185
T47D TGX221
3.1623
PI3Kb
PI3K/mTOR
 0.9245 -0.00077
T47D TGX221
10.0
PI3Kb
PI3K/mTOR
 0.7986 0.00168
T47D Torin2
0.00031623
mTOR/ATM/ATR
PI3K/mTOR
 1.0340 -0.00019
T47D Torin2
0.001
mTOR/ATM/ATR
PI3K/mTOR
 0.9543 -0.00159
T47D Torin2
0.031623
mTOR/ATM/ATR
PI3K/mTOR
 0.1112 0.02794
T47D Torin2
0.1
mTOR/ATM/ATR
PI3K/mTOR
 0.0792 0.03630
T47D Torin2
1.0
mTOR/ATM/ATR
PI3K/mTOR
 0.0099 0.07041
T47D Everolimus
0.001
mTOR1
PI3K/mTOR
 0.4754 0.00865
T47D Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.3554 0.01646
T47D Everolimus
1.0
mTOR1
PI3K/mTOR
 0.3599 0.01312
T47D Everolimus
10.0
mTOR1
PI3K/mTOR
 0.2975 0.02128
T47D INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 1.0271 0.00098
T47D INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.2753 0.01646
T47D INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.0771 0.02991
T47D INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.0187 0.03759
T47D INK-128
1.0
mTORC1/2
PI3K/mTOR
 0.0081 0.03583
T47D PF-4708671
0.01
p70S6K
PI3K/mTOR
 1.0634 0.00005
T47D PF-4708671
0.031623
p70S6K
PI3K/mTOR
 1.0128 0.00308
T47D Buparlisib
1.0
pan PI3K
PI3K/mTOR
 0.1266 0.03434
T47D Buparlisib
0.31623
pan PI3K
PI3K/mTOR
 0.4339 0.01153