Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SUM159PT Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.6445 -0.00069
SUM159PT Everolimus
1.0
mTOR1
PI3K/mTOR
 0.6606 -0.00006
SUM159PT Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.6950 -0.00397
SUM159PT Everolimus
10.0
mTOR1
PI3K/mTOR
 0.6876 -0.00351
SUM159PT INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 1.0024 -0.00056
SUM159PT INK-128
0.001
mTORC1/2
PI3K/mTOR
 0.9923 -0.00191
SUM159PT INK-128
0.0031623
mTORC1/2
PI3K/mTOR
 0.9494 -0.00464
SUM159PT INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.6910 -0.00574
SUM159PT INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.3511 0.00165
SUM159PT INK-128
0.1
mTORC1/2
PI3K/mTOR
 0.2370 0.00060
SUM159PT INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.1756 0.00697
SUM159PT INK-128
1.0
mTORC1/2
PI3K/mTOR
 0.1618 0.00491
SUM159PT INK-128
3.1623
mTORC1/2
PI3K/mTOR
 0.1504 0.00233
SUM159PT PF-4708671
0.001
p70S6K
PI3K/mTOR
 0.9978 0.00214
SUM159PT PF-4708671
0.0031623
p70S6K
PI3K/mTOR
 1.0081 0.00481
SUM159PT PF-4708671
0.01
p70S6K
PI3K/mTOR
 1.0123 0.00284
SUM159PT PF-4708671
0.031623
p70S6K
PI3K/mTOR
 1.0011 0.00244
SUM159PT PF-4708671
0.1
p70S6K
PI3K/mTOR
 0.9916 0.00140
SUM159PT PF-4708671
0.31623
p70S6K
PI3K/mTOR
 0.9855 0.00217
SUM159PT PF-4708671
1.0
p70S6K
PI3K/mTOR
 0.9498 0.00644
SUM159PT PF-4708671
3.1623
p70S6K
PI3K/mTOR
 0.9180 0.01471
SUM159PT PF-4708671
10.0
p70S6K
PI3K/mTOR
 0.7309 0.07832
SUM159PT Buparlisib
0.001
pan PI3K
PI3K/mTOR
 1.0009 0.00557
SUM159PT Buparlisib
0.0031623
pan PI3K
PI3K/mTOR
 1.0105 0.00215
SUM159PT Buparlisib
0.01
pan PI3K
PI3K/mTOR
 1.0128 -0.00096