Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1428 Etoposide
10.0
Topo II
Chemotherapy
 -0.0320 0.18973
HCC1428 Dasatinib
0.001
BCR/ABL
MAPK/nRTK
 0.9452 0.00059
HCC1428 Dasatinib
0.0031623
BCR/ABL
MAPK/nRTK
 1.0076 -0.00046
HCC1428 Dasatinib
0.01
BCR/ABL
MAPK/nRTK
 0.8331 0.00872
HCC1428 Dasatinib
0.031623
BCR/ABL
MAPK/nRTK
 0.7613 0.01180
HCC1428 Dasatinib
0.1
BCR/ABL
MAPK/nRTK
 0.7639 0.01421
HCC1428 Dasatinib
0.31623
BCR/ABL
MAPK/nRTK
 0.6534 0.02260
HCC1428 Dasatinib
1.0
BCR/ABL
MAPK/nRTK
 0.5899 0.02428
HCC1428 Dasatinib
3.1623
BCR/ABL
MAPK/nRTK
 0.5784 0.04640
HCC1428 Dasatinib
10.0
BCR/ABL
MAPK/nRTK
 0.5811 0.04450
HCC1428 Trametinib
0.0001
MEK
MAPK/nRTK
 1.0473 -0.00317
HCC1428 Trametinib
0.00031623
MEK
MAPK/nRTK
 1.0019 0.00030
HCC1428 Trametinib
0.001
MEK
MAPK/nRTK
 1.1077 0.00345
HCC1428 Trametinib
0.0031623
MEK
MAPK/nRTK
 0.9665 -0.00435
HCC1428 Trametinib
0.01
MEK
MAPK/nRTK
 1.0225 0.00107
HCC1428 Trametinib
0.031623
MEK
MAPK/nRTK
 0.8390 0.00898
HCC1428 Trametinib
0.1
MEK
MAPK/nRTK
 0.7464 0.00989
HCC1428 Trametinib
0.31623
MEK
MAPK/nRTK
 0.8292 0.00459
HCC1428 Trametinib
1.0
MEK
MAPK/nRTK
 0.8152 0.00132
HCC1428 Saracatinib
0.001
SRC
MAPK/nRTK
 1.0236 0.00091
HCC1428 Saracatinib
0.0031623
SRC
MAPK/nRTK
 1.0987 -0.00012
HCC1428 Saracatinib
0.01
SRC
MAPK/nRTK
 1.0720 -0.00277
HCC1428 Saracatinib
0.031623
SRC
MAPK/nRTK
 0.9964 -0.00112
HCC1428 Saracatinib
0.1
SRC
MAPK/nRTK
 0.9897 0.00716
HCC1428 Saracatinib
0.31623
SRC
MAPK/nRTK
 0.8890 0.00703