Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SUM149PT Torin2
0.0001
mTOR/ATM/ATR
PI3K/mTOR
 0.9944 0.00191
SUM149PT Torin2
0.00031623
mTOR/ATM/ATR
PI3K/mTOR
 1.0357 0.00014
SUM149PT Torin2
0.001
mTOR/ATM/ATR
PI3K/mTOR
 0.9754 -0.00095
SUM149PT Torin2
0.0031623
mTOR/ATM/ATR
PI3K/mTOR
 0.9443 -0.00274
SUM149PT Torin2
0.01
mTOR/ATM/ATR
PI3K/mTOR
 0.8687 -0.00036
SUM149PT Torin2
0.031623
mTOR/ATM/ATR
PI3K/mTOR
 0.7126 0.00320
SUM149PT Torin2
0.1
mTOR/ATM/ATR
PI3K/mTOR
 0.5498 0.02501
SUM149PT Torin2
0.31623
mTOR/ATM/ATR
PI3K/mTOR
 0.3530 0.09704
SUM149PT Torin2
1.0
mTOR/ATM/ATR
PI3K/mTOR
 0.0001 0.32800
SUM149PT Everolimus
0.001
mTOR1
PI3K/mTOR
 0.8569 0.01038
SUM149PT Everolimus
0.0031623
mTOR1
PI3K/mTOR
 0.8402 0.00941
SUM149PT Everolimus
0.01
mTOR1
PI3K/mTOR
 0.8042 0.01127
SUM149PT Everolimus
0.031623
mTOR1
PI3K/mTOR
 0.7914 0.00613
SUM149PT Everolimus
0.1
mTOR1
PI3K/mTOR
 0.7753 0.01543
SUM149PT Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.8050 0.00848
SUM149PT Everolimus
1.0
mTOR1
PI3K/mTOR
 0.8149 0.00929
SUM149PT Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.7688 0.00796
SUM149PT Everolimus
10.0
mTOR1
PI3K/mTOR
 0.7389 0.00963
SUM149PT INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 0.9969 -0.00213
SUM149PT INK-128
0.001
mTORC1/2
PI3K/mTOR
 1.0077 -0.00129
SUM149PT INK-128
0.0031623
mTORC1/2
PI3K/mTOR
 0.9298 -0.00457
SUM149PT INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.8112 0.00642
SUM149PT INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.6698 0.00324
SUM149PT INK-128
0.1
mTORC1/2
PI3K/mTOR
 0.5609 0.00976
SUM149PT INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.4496 0.00758