Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MCF 10A Bleomycin
0.0033333
Radiation
Misc
 0.9744 -0.00150
MCF 10A Bleomycin
0.01
Radiation
Misc
 0.9373 0.00092
MCF 10A Bleomycin
0.031667
Radiation
Misc
 0.8302 0.00839
MCF 10A Bleomycin
0.1
Radiation
Misc
 0.6487 0.04327
MCF 10A Bleomycin
0.31623
Radiation
Misc
 0.3823 0.08077
MCF 10A Bleomycin
1.0
Radiation
Misc
 0.1151 0.14688
MCF 10A Bleomycin
3.1623
Radiation
Misc
 0.0378 0.14909
MCF 10A Bleomycin
10.0
Radiation
Misc
 0.0402 0.19939
MCF 10A Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0022 -0.00043
MCF 10A Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0004 0.00065
MCF 10A Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0017 0.00024
MCF 10A Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0078 0.00047
MCF 10A Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9958 -0.00108
MCF 10A Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.9681 -0.00119
MCF 10A Ipatasertib
1.0
AKT
PI3K/mTOR
 0.9214 -0.00401
MCF 10A Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.8001 -0.00568
MCF 10A Ipatasertib
10.0
AKT
PI3K/mTOR
 0.6472 -0.00617
MCF 10A Alpelisib
0.001
PI3Ka
PI3K/mTOR
 1.0008 -0.00008
MCF 10A Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 0.9996 0.00096
MCF 10A Alpelisib
0.01
PI3Ka
PI3K/mTOR
 0.9815 -0.00106
MCF 10A Alpelisib
0.031623
PI3Ka
PI3K/mTOR
 0.9599 -0.00245
MCF 10A Alpelisib
0.1
PI3Ka
PI3K/mTOR
 0.9214 -0.00391
MCF 10A Alpelisib
0.31623
PI3Ka
PI3K/mTOR
 0.8851 -0.00428
MCF 10A Alpelisib
1.0
PI3Ka
PI3K/mTOR
 0.8204 -0.00590
MCF 10A Alpelisib
3.1623
PI3Ka
PI3K/mTOR
 0.7419 -0.00534