LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 23.60 | 11.9 | 0.0306 | 0.0309 | -0.1485 | -0.0099 | 1.0173 | 0.5273 |
| MCF 10A-H2B-mCherry | Neratinib | 25.30 | 11.9 | 0.0433 | 0.0502 | -0.1661 | -0.0752 | 1.0775 | 0.5110 |
| MCF 10A-H2B-mCherry | Neratinib | 27.00 | 11.9 | 0.06 | 0.0926 | -0.2624 | -0.2032 | 1.0642 | 0.4961 |
| MCF 10A-H2B-mCherry | Neratinib | 28.71 | 11.9 | 0.0762 | 0.1036 | -0.2844 | -0.1900 | 1.2246 | 0.4738 |
| MCF 10A-H2B-mCherry | Neratinib | 30.41 | 11.9 | 0.1 | 0.1221 | -0.2689 | -0.1406 | 1.2401 | 0.4251 |
| MCF 10A-H2B-mCherry | Neratinib | 32.11 | 11.9 | 0.1058 | 0.1406 | -0.2971 | -0.1544 | 1.4512 | 0.4115 |
| MCF 10A-H2B-mCherry | Neratinib | 33.82 | 11.9 | 0.1427 | 0.3322 | -0.3416 | -0.4578 | 0.8756 | 0.3922 |
| MCF 10A-H2B-mCherry | Neratinib | 35.52 | 11.9 | 0.1339 | 0.274 | -0.3707 | -0.4169 | 0.8860 | 0.4057 |
| MCF 10A-H2B-mCherry | Neratinib | 37.23 | 11.9 | 0.1793 | 0.5696 | -0.4836 | -0.7708 | 0.8358 | 0.3897 |
| MCF 10A-H2B-mCherry | Neratinib | 38.93 | 11.9 | 0.2348 | 0.6201 | -0.3998 | -0.6314 | 0.9318 | 0.3362 |
| MCF 10A-H2B-mCherry | Neratinib | 40.63 | 11.9 | 0.203 | 0.3326 | -0.3677 | -0.3638 | 1.0921 | 0.3367 |
| MCF 10A-H2B-mCherry | Neratinib | 42.33 | 11.9 | 0.1842 | 0.2157 | -0.4156 | -0.1692 | 2.2882 | 0.3361 |
| MCF 10A-H2B-mCherry | Neratinib | 44.03 | 11.9 | 0.223 | 0.3193 | -0.3749 | -0.3064 | 1.4065 | 0.3229 |
| MCF 10A-H2B-mCherry | Neratinib | 45.74 | 11.9 | 0.1851 | 0.2055 | -0.2997 | -0.1135 | 1.8342 | 0.3371 |
| MCF 10A-H2B-mCherry | Neratinib | 47.45 | 11.9 | 0.2157 | 0.2505 | -0.2998 | -0.0903 | 2.1956 | 0.2935 |
| MCF 10A-H2B-mCherry | Neratinib | 49.15 | 11.9 | 0.3313 | 0.6933 | -0.3296 | -0.4583 | 1.0994 | 0.2787 |
| MCF 10A-H2B-mCherry | Neratinib | 50.86 | 11.9 | 0.3031 | 0.8273 | -0.4388 | -0.5640 | 1.3591 | 0.2906 |
| MCF 10A-H2B-mCherry | Neratinib | 52.56 | 11.9 | 0.3365 | 0.9634 | -0.5476 | -0.7159 | 1.2704 | 0.2806 |
| MCF 10A-H2B-mCherry | Neratinib | 54.25 | 11.9 | 0.45 | 1.3349 | -0.6369 | -0.9728 | 1.2215 | 0.2717 |
| MCF 10A-H2B-mCherry | Neratinib | 55.97 | 11.9 | 0.4248 | 1.1732 | -0.6983 | -1.0000 | 1.2159 | 0.2772 |
| MCF 10A-H2B-mCherry | Neratinib | 57.67 | 11.9 | 0.4637 | 1.3072 | -0.6943 | -1.0000 | 1.2533 | 0.2654 |
| MCF 10A-H2B-mCherry | Neratinib | 59.37 | 11.9 | 0.3227 | 0.5545 | -0.7328 | -0.7073 | 1.5946 | 0.3292 |
| MCF 10A-H2B-mCherry | Neratinib | 61.08 | 11.9 | 0.3193 | 0.4739 | -0.7166 | -0.5803 | 1.8981 | 0.3308 |
| MCF 10A-H2B-mCherry | Neratinib | 62.78 | 11.9 | 0.3552 | 0.4164 | -0.6718 | -0.4322 | 3.7868 | 0.3386 |
| MCF 10A-H2B-mCherry | Neratinib | 64.49 | 11.9 | 0.3607 | 0.4759 | -0.7163 | -0.5720 | 3.3539 | 0.3509 |