LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)

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Cell Small Molecule Time Point (hr) Time Interval (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Neratinib 66.19 11.9
0.3419
0.382
 -0.7691 -0.3742 4.9998 0.3397
MCF 10A-H2B-mCherry Neratinib 67.89 11.9
0.459
0.8951
 -0.6805 -0.7165 3.0736 0.3488
MCF 10A-H2B-mCherry Neratinib 69.60 11.9
0.6006
1.0581
 -0.8627 -0.8773 3.5601 0.3744
MCF 10A-H2B-mCherry Neratinib 71.30 11.9
Inf
Inf
 -0.7067 -0.7067 0.0000 0.3198
MCF 10A-H2B-mCherry Neratinib 73.49 11.9
Inf
Inf
 -1.0000 -1.0000 0.0000 0.4286
MCF 10A-H2B-mCherry Neratinib 76.90 11.9
Inf
Inf
 -1.0000 -1.0000 0.0000 0.3500
MCF 10A-H2B-mCherry Neratinib 80.31 11.9
Inf
Inf
 -1.0000 -1.0000 0.0000 0.3828
MCF 10A-H2B-mCherry Neratinib 85.43 11.9
Inf
Inf
 0.1308 0.1308 0.0000 0.4931
MCF 10A-H2B-mCherry Neratinib 85.43 12.0
Inf
Inf
 -0.8789 -0.8789 0.0000 0.5982
MCF 10A-H2B-mCherry Neratinib 89.69 11.9
Inf
Inf
 1.0500 1.0500 0.0000 0.5370
MCF 10A-H2B-mCherry Palbociclib 15.08 11.9
Inf
Inf
 0.1532 0.1532 0.0000 0.4065
MCF 10A-H2B-mCherry Palbociclib 16.79 11.9
Inf
Inf
 0.1194 -0.3957 0.0878 0.4436
MCF 10A-H2B-mCherry Palbociclib 18.49 11.9
Inf
Inf
 0.0520 -0.4305 0.1045 0.4625
MCF 10A-H2B-mCherry Palbociclib 20.19 11.9
0.1053
23.8386
 0.1006 -0.3621 0.3848 0.4707
MCF 10A-H2B-mCherry Palbociclib 21.90 11.9
0.1028
3.6973
 0.0917 -0.2900 0.4483 0.4878
MCF 10A-H2B-mCherry Palbociclib 23.60 11.9
0.1293
4.9077
 0.0535 -0.4107 0.6847 0.4909
MCF 10A-H2B-mCherry Palbociclib 25.30 11.9
0.1483
0.1392
 0.0934 0.1739 3.2748 0.4447
MCF 10A-H2B-mCherry Palbociclib 27.00 11.9
0.1687
0.1544
 0.0778 0.1703 3.2433 0.4239
MCF 10A-H2B-mCherry Palbociclib 28.71 11.9
0.1921
0.1743
 0.0502 0.1399 2.7597 0.4197
MCF 10A-H2B-mCherry Palbociclib 30.41 11.9
0.2416
0.1935
 0.0651 0.1034 1.0430 0.3982
MCF 10A-H2B-mCherry Palbociclib 32.11 11.9
0.3007
0.3037
 0.0493 0.0030 0.8310 0.3877
MCF 10A-H2B-mCherry Palbociclib 33.82 11.9
0.3333
0.5123
 0.0442 -0.0905 0.6772 0.3797
MCF 10A-H2B-mCherry Palbociclib 35.52 11.9
0.3131
0.7629
 0.0347 -0.1254 0.6828 0.3821
MCF 10A-H2B-mCherry Palbociclib 37.23 11.9
0.3111
1.7194
 0.0455 -0.2613 0.6493 0.3859
MCF 10A-H2B-mCherry Palbociclib 38.93 11.9
0.3215
0.6362
 0.0367 -0.0968 0.8082 0.3640