LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 76.90 | 11.9 | Inf | Inf | -0.8342 | -0.8342 | 0.0000 | 0.7051 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.31 | 11.9 | Inf | Inf | -0.8783 | -0.8783 | 0.0000 | 0.8067 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 11.9 | Inf | Inf | -0.9117 | -0.9117 | 0.0000 | 0.9543 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 12.0 | Inf | Inf | -0.8540 | -0.8540 | 0.0000 | 0.9401 |
| MCF 10A-H2B-mCherry | Dasatinib | 89.69 | 11.9 | Inf | Inf | -0.9466 | -0.9466 | 0.0000 | 1.1164 |
| MCF 10A-H2B-mCherry | Etoposide | 15.08 | 11.9 | Inf | Inf | 0.0410 | -0.3362 | 0.4618 | 0.2363 |
| MCF 10A-H2B-mCherry | Etoposide | 16.79 | 11.9 | 2.2187 | 15.6011 | 0.0196 | -1.0000 | 0.6178 | 0.2349 |
| MCF 10A-H2B-mCherry | Etoposide | 18.49 | 11.9 | 1.6291 | 11.8949 | 0.0238 | -1.0000 | 0.5835 | 0.2602 |
| MCF 10A-H2B-mCherry | Etoposide | 20.19 | 11.9 | 1.0484 | 6.2551 | 0.0379 | -0.5651 | 0.6316 | 0.2770 |
| MCF 10A-H2B-mCherry | Etoposide | 21.90 | 11.9 | 0.6499 | 3.6752 | 0.0253 | -0.3594 | 0.7066 | 0.3075 |
| MCF 10A-H2B-mCherry | Etoposide | 23.60 | 11.9 | 0.4333 | 0.3681 | 0.0325 | 0.0929 | 0.9623 | 0.3221 |
| MCF 10A-H2B-mCherry | Etoposide | 25.30 | 11.9 | 0.3804 | 0.3361 | 0.0269 | 0.0627 | 1.0177 | 0.3559 |
| MCF 10A-H2B-mCherry | Etoposide | 27.00 | 11.9 | 0.3204 | 0.3087 | 0.0279 | 0.0223 | 1.0652 | 0.3875 |
| MCF 10A-H2B-mCherry | Etoposide | 28.71 | 11.9 | 0.282 | 0.2635 | 0.0303 | 0.0409 | 1.1655 | 0.3976 |
| MCF 10A-H2B-mCherry | Etoposide | 30.41 | 11.9 | 0.2534 | 0.2242 | 0.0315 | 0.0751 | 1.2997 | 0.3958 |
| MCF 10A-H2B-mCherry | Etoposide | 32.11 | 11.9 | 0.2448 | 0.2218 | 0.0235 | 0.0692 | 1.4555 | 0.3981 |
| MCF 10A-H2B-mCherry | Etoposide | 33.82 | 11.9 | 0.2471 | 0.2329 | 0.0176 | 0.0438 | 1.5507 | 0.4037 |
| MCF 10A-H2B-mCherry | Etoposide | 35.52 | 11.9 | 0.223 | 0.2229 | 0.0131 | 0.0028 | 1.4052 | 0.4283 |
| MCF 10A-H2B-mCherry | Etoposide | 37.23 | 11.9 | 0.2364 | 0.2371 | 0.0002 | 0.0031 | 1.4891 | 0.4201 |
| MCF 10A-H2B-mCherry | Etoposide | 38.93 | 11.9 | 0.2488 | 0.2463 | -0.0009 | 0.0169 | 1.3972 | 0.4009 |
| MCF 10A-H2B-mCherry | Etoposide | 40.63 | 11.9 | 0.2294 | 0.2347 | -0.0234 | 0.0091 | 1.5424 | 0.4124 |
| MCF 10A-H2B-mCherry | Etoposide | 42.33 | 11.9 | 0.2077 | 0.211 | 0.0213 | 0.0049 | 1.4089 | 0.4300 |
| MCF 10A-H2B-mCherry | Etoposide | 44.03 | 11.9 | 0.2011 | 0.2131 | -0.0216 | -0.0155 | 1.3834 | 0.4395 |
| MCF 10A-H2B-mCherry | Etoposide | 45.74 | 11.9 | 0.1716 | 0.1929 | -0.0316 | -0.0447 | 1.3335 | 0.4647 |
| MCF 10A-H2B-mCherry | Etoposide | 47.45 | 11.9 | 0.1862 | 0.2031 | -0.0090 | -0.0220 | 1.4962 | 0.4441 |