LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
---|---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Dasatinib | 32.11 | 11.9 | 0.3734 | 6.0886 | 0.0171 | -0.4728 | 0.5261 | 0.3838 |
MCF 10A-H2B-mCherry | Dasatinib | 33.82 | 11.9 | 0.3689 | 4.7321 | 0.0048 | -0.4354 | 0.5695 | 0.3769 |
MCF 10A-H2B-mCherry | Dasatinib | 35.52 | 11.9 | 0.3039 | 5.21 | -0.0202 | -0.4646 | 0.5438 | 0.4006 |
MCF 10A-H2B-mCherry | Dasatinib | 37.23 | 11.9 | 0.3431 | 5.4874 | -0.0704 | -0.4815 | 0.5455 | 0.3950 |
MCF 10A-H2B-mCherry | Dasatinib | 38.93 | 11.9 | 0.4278 | 5.3401 | -0.0964 | -0.5198 | 0.5259 | 0.3783 |
MCF 10A-H2B-mCherry | Dasatinib | 40.63 | 11.9 | 0.4391 | 4.4559 | -0.1289 | -0.5327 | 0.5278 | 0.3762 |
MCF 10A-H2B-mCherry | Dasatinib | 42.33 | 11.9 | 0.4064 | 4.0686 | -0.1481 | -0.5461 | 0.5225 | 0.3847 |
MCF 10A-H2B-mCherry | Dasatinib | 44.03 | 11.9 | 0.4123 | 4.1739 | -0.1412 | -0.5818 | 0.4871 | 0.3859 |
MCF 10A-H2B-mCherry | Dasatinib | 45.74 | 11.9 | 0.442 | 4.8294 | -0.1569 | -0.6440 | 0.4592 | 0.3860 |
MCF 10A-H2B-mCherry | Dasatinib | 47.45 | 11.9 | 0.6525 | 4.8106 | -0.2148 | -0.7541 | 0.4818 | 0.3498 |
MCF 10A-H2B-mCherry | Dasatinib | 49.15 | 11.9 | 0.8818 | 11.0074 | -0.2493 | -1.0000 | 0.4675 | 0.3252 |
MCF 10A-H2B-mCherry | Dasatinib | 50.86 | 11.9 | 1.1058 | 12.4343 | -0.2680 | -1.0000 | 0.4767 | 0.3013 |
MCF 10A-H2B-mCherry | Dasatinib | 52.56 | 11.9 | 1.4789 | 9.4423 | -0.2797 | -1.0000 | 0.6283 | 0.2800 |
MCF 10A-H2B-mCherry | Dasatinib | 54.25 | 11.9 | 2.4281 | 8.3283 | -0.3369 | -1.0000 | 1.0304 | 0.2327 |
MCF 10A-H2B-mCherry | Dasatinib | 55.97 | 11.9 | 4.1363 | 6.7932 | -0.4294 | -1.0000 | 3.3320 | 0.2248 |
MCF 10A-H2B-mCherry | Dasatinib | 57.67 | 11.9 | 4.4368 | 6.0598 | -0.4485 | -0.8032 | 4.8913 | 0.2064 |
MCF 10A-H2B-mCherry | Dasatinib | 59.37 | 11.9 | 4.4684 | 6.0639 | -0.4145 | -0.7730 | 5.0000 | 0.2216 |
MCF 10A-H2B-mCherry | Dasatinib | 61.08 | 11.9 | 2.484 | 4.7737 | -0.4178 | -0.7602 | 3.0185 | 0.2572 |
MCF 10A-H2B-mCherry | Dasatinib | 62.78 | 11.9 | 2.0981 | 4.2239 | -0.4665 | -0.8011 | 2.9618 | 0.2741 |
MCF 10A-H2B-mCherry | Dasatinib | 64.49 | 11.9 | 1.8515 | 4.5604 | -0.5153 | -0.8450 | 2.8465 | 0.2907 |
MCF 10A-H2B-mCherry | Dasatinib | 66.19 | 11.9 | 1.4145 | 4.3056 | -0.5860 | -0.9014 | 2.7702 | 0.3291 |
MCF 10A-H2B-mCherry | Dasatinib | 67.89 | 11.9 | Inf | Inf | -0.6482 | -0.9446 | 0.2134 | 0.3543 |
MCF 10A-H2B-mCherry | Dasatinib | 69.60 | 11.9 | Inf | Inf | -0.7093 | -0.7093 | 0.0000 | 0.3803 |
MCF 10A-H2B-mCherry | Dasatinib | 71.30 | 11.9 | Inf | Inf | -0.7768 | -0.7768 | 0.0000 | 0.4315 |
MCF 10A-H2B-mCherry | Dasatinib | 73.49 | 11.9 | Inf | Inf | -0.7187 | -0.7187 | 0.0000 | 0.6199 |