LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 36.16 | 11.8 | 0.1155 | 0.1569 | -0.2429 | -0.2540 | 1.3144 | 0.4403 |
| MCF 10A-H2B-mCherry | Neratinib | 38.13 | 11.8 | 0.149 | 0.1814 | -0.2264 | -0.2007 | 1.6932 | 0.4015 |
| MCF 10A-H2B-mCherry | Neratinib | 40.10 | 11.8 | 0.1666 | 0.1751 | -0.2056 | -0.0606 | 3.0455 | 0.3506 |
| MCF 10A-H2B-mCherry | Neratinib | 42.07 | 11.8 | 0.1778 | 0.1791 | -0.1480 | 0.0027 | 4.6136 | 0.3474 |
| MCF 10A-H2B-mCherry | Neratinib | 44.04 | 11.8 | 0.2075 | 0.2202 | -0.1442 | -0.0168 | 3.5213 | 0.3305 |
| MCF 10A-H2B-mCherry | Neratinib | 46.00 | 11.8 | 0.2402 | 0.2637 | -0.1157 | -0.0213 | 3.5611 | 0.3155 |
| MCF 10A-H2B-mCherry | Neratinib | 47.98 | 11.8 | 0.281 | 0.3385 | -0.1719 | -0.0939 | 2.8142 | 0.3059 |
| MCF 10A-H2B-mCherry | Neratinib | 49.95 | 11.8 | 0.304 | 0.3705 | -0.1991 | -0.1157 | 3.0361 | 0.3028 |
| MCF 10A-H2B-mCherry | Neratinib | 51.92 | 11.8 | 0.3001 | 0.32 | -0.2059 | -0.0987 | 3.2843 | 0.3040 |
| MCF 10A-H2B-mCherry | Neratinib | 53.89 | 11.8 | 0.3477 | 0.381 | -0.2664 | -0.1387 | 3.7292 | 0.2856 |
| MCF 10A-H2B-mCherry | Neratinib | 56.36 | 12.8 | 0.3409 | 0.3863 | -0.2782 | -0.2034 | 3.7838 | 0.2979 |
| MCF 10A-H2B-mCherry | Neratinib | 58.33 | 12.8 | 0.3234 | 0.371 | -0.3872 | -0.2928 | 3.9380 | 0.3253 |
| MCF 10A-H2B-mCherry | Neratinib | 60.30 | 12.8 | 0.3735 | 0.4891 | -0.4937 | -0.4609 | 2.3613 | 0.3388 |
| MCF 10A-H2B-mCherry | Neratinib | 62.27 | 12.8 | 0.3897 | 0.5562 | -0.5658 | -0.5865 | 2.1736 | 0.3542 |
| MCF 10A-H2B-mCherry | Neratinib | 64.24 | 12.8 | 0.4495 | 0.6532 | -0.7536 | -0.7620 | 3.3315 | 0.3860 |
| MCF 10A-H2B-mCherry | Neratinib | 66.21 | 12.8 | 0.4418 | 0.7084 | -0.7114 | -0.8082 | 3.1712 | 0.3995 |
| MCF 10A-H2B-mCherry | Neratinib | 68.68 | 11.8 | 0.3083 | 0.3924 | -0.7474 | -0.5509 | 4.1022 | 0.4356 |
| MCF 10A-H2B-mCherry | Neratinib | 70.65 | 11.8 | 0.409 | 0.8755 | -0.7838 | -0.9606 | 2.1901 | 0.4163 |
| MCF 10A-H2B-mCherry | Neratinib | 72.62 | 11.8 | Inf | Inf | -0.6829 | -0.9987 | 0.4021 | 0.4642 |
| MCF 10A-H2B-mCherry | Neratinib | 74.59 | 11.8 | Inf | Inf | -0.7181 | -0.9989 | 0.6470 | 0.4952 |
| MCF 10A-H2B-mCherry | Neratinib | 76.56 | 11.8 | Inf | Inf | -0.6488 | -0.9900 | 0.4587 | 0.4979 |
| MCF 10A-H2B-mCherry | Neratinib | 78.53 | 11.8 | Inf | Inf | -0.7553 | -0.9963 | 1.0525 | 0.4438 |
| MCF 10A-H2B-mCherry | Neratinib | 80.50 | 11.8 | Inf | Inf | -0.3030 | -0.3030 | 0.0000 | 0.4783 |
| MCF 10A-H2B-mCherry | Neratinib | 82.47 | 11.8 | Inf | Inf | -0.2038 | -0.2038 | 0.0000 | 0.4483 |
| MCF 10A-H2B-mCherry | Neratinib | 84.44 | 11.8 | Inf | Inf | -0.2686 | -0.2686 | 0.0000 | 0.4519 |