LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)

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Cell Small Molecule Time Point (hr) Time Interval (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Neratinib 86.41 11.8
Inf
Inf
 0.6220 0.6220 0.0000 0.3526
MCF 10A-H2B-mCherry Neratinib 88.39 11.8
Inf
Inf
 0.8099 0.8099 0.0000 0.3692
MCF 10A-H2B-mCherry Palbociclib 14.50 11.8
0.1749
0.0968
 0.2268 0.3503 2.9383 0.3639
MCF 10A-H2B-mCherry Palbociclib 16.47 11.8
Inf
Inf
 0.1333 0.1764 0.4900 0.4113
MCF 10A-H2B-mCherry Palbociclib 18.43 11.8
Inf
Inf
 0.0844 0.1016 0.4161 0.4274
MCF 10A-H2B-mCherry Palbociclib 20.40 11.8
Inf
Inf
 0.0818 0.0679 0.3009 0.4196
MCF 10A-H2B-mCherry Palbociclib 22.37 11.8
Inf
Inf
 0.0799 0.0010 0.2557 0.3981
MCF 10A-H2B-mCherry Palbociclib 24.34 11.8
0.3032
1.183
 0.0538 -0.0590 0.7314 0.3869
MCF 10A-H2B-mCherry Palbociclib 26.31 11.8
0.3791
2.4973
 0.0580 -0.1371 0.8841 0.3635
MCF 10A-H2B-mCherry Palbociclib 28.28 11.8
0.4036
8.1899
 0.0432 -0.3718 0.5514 0.3797
MCF 10A-H2B-mCherry Palbociclib 30.24 11.8
0.4493
10.2532
 0.0620 -0.3916 0.6457 0.3642
MCF 10A-H2B-mCherry Palbociclib 32.22 11.8
0.515
8.8974
 0.0517 -0.4049 0.6119 0.3518
MCF 10A-H2B-mCherry Palbociclib 34.19 11.8
0.6129
9.0593
 0.0536 -0.4395 0.5605 0.3342
MCF 10A-H2B-mCherry Palbociclib 36.16 11.8
0.5403
8.1051
 0.0970 -0.4551 0.5656 0.3518
MCF 10A-H2B-mCherry Palbociclib 38.13 11.8
0.4909
0.6089
 0.0816 -0.0159 0.6887 0.3527
MCF 10A-H2B-mCherry Palbociclib 40.10 11.8
0.3048
0.2526
 0.0977 0.1916 2.9421 0.3204
MCF 10A-H2B-mCherry Palbociclib 42.07 11.8
0.3232
0.3135
 0.0817 0.1262 2.8482 0.3335
MCF 10A-H2B-mCherry Palbociclib 44.04 11.8
0.3482
0.3213
 0.0675 0.1504 2.8898 0.3203
MCF 10A-H2B-mCherry Palbociclib 46.00 11.8
0.7045
0.9271
 0.0729 -0.0602 0.7924 0.3190
MCF 10A-H2B-mCherry Palbociclib 47.98 11.8
1.0859
1.434
 0.0526 -0.0460 1.0763 0.2691
MCF 10A-H2B-mCherry Palbociclib 49.95 11.8
1.5871
2.9544
 0.1121 -0.1626 2.7729 0.2429
MCF 10A-H2B-mCherry Palbociclib 51.92 11.8
1.9664
2.097
 0.0937 0.1019 3.0700 0.2349
MCF 10A-H2B-mCherry Palbociclib 53.89 11.8
3.0804
6.8008
 0.0928 -0.4511 1.5959 0.2138
MCF 10A-H2B-mCherry Palbociclib 56.36 12.8
4.6212
2.9453
 0.2561 0.2318 2.3448 0.1793
MCF 10A-H2B-mCherry Palbociclib 58.33 12.8
Inf
2.7842
 0.2336 0.2251 3.3390 0.1717