LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 76.38 | 13.4 | Inf | Inf | 0.9533 | 0.9533 | 0.0000 | -0.0076 |
| MCF 10A-H2B-mCherry | Alpelisib | 71.94 | 13.4 | Inf | Inf | 0.9804 | 0.9804 | 0.0000 | -0.0105 |
| MCF 10A-H2B-mCherry | Alpelisib | 78.60 | 13.4 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0077 |
| MCF 10A-H2B-mCherry | Alpelisib | 74.16 | 13.4 | Inf | Inf | 1.0285 | 1.0285 | 0.0000 | -0.0023 |
| MCF 10A-H2B-mCherry | Alpelisib | 69.71 | 13.4 | Inf | Inf | 0.8659 | 0.8659 | 0.0000 | 0.0193 |
| MCF 10A-H2B-mCherry | Alpelisib | 80.82 | 13.4 | Inf | Inf | 0.9804 | 0.9804 | 0.0000 | -0.0023 |
| MCF 10A-H2B-mCherry | Alpelisib | 38.59 | 13.3 | Inf | 659.7431 | 0.7083 | -0.8898 | 0.4399 | 0.0784 |
| MCF 10A-H2B-mCherry | Dasatinib | 31.92 | 13.3 | 0.473 | 2.4894 | -0.0595 | -0.5851 | 0.4682 | 0.3814 |
| MCF 10A-H2B-mCherry | Dasatinib | 36.36 | 13.3 | 0.5258 | 2.9059 | -0.0324 | -0.6249 | 0.4713 | 0.3740 |
| MCF 10A-H2B-mCherry | Dasatinib | 34.14 | 13.3 | 0.5075 | 2.7807 | -0.0344 | -0.6161 | 0.4727 | 0.3748 |
| MCF 10A-H2B-mCherry | Dasatinib | 38.59 | 13.3 | 0.5386 | 3.3837 | -0.0418 | -0.7129 | 0.4750 | 0.3711 |
| MCF 10A-H2B-mCherry | Alpelisib | 36.36 | 13.3 | 42.9745 | 417.2033 | 0.6921 | -0.9983 | 0.4876 | 0.0807 |
| MCF 10A-H2B-mCherry | Dasatinib | 40.81 | 13.3 | 0.6387 | 3.8735 | -0.0618 | -0.7504 | 0.4977 | 0.3511 |
| MCF 10A-H2B-mCherry | Alpelisib | 15.91 | 13.5 | 18.5716 | 168.3795 | 0.5685 | -1.0000 | 0.4983 | 0.1166 |
| MCF 10A-H2B-mCherry | Alpelisib | 34.14 | 13.3 | 33.6323 | 138.7884 | 0.6705 | -0.6260 | 0.5249 | 0.0816 |
| MCF 10A-H2B-mCherry | Dasatinib | 29.70 | 13.3 | 0.4516 | 1.1873 | -0.0290 | -0.3307 | 0.5282 | 0.3756 |
| MCF 10A-H2B-mCherry | Dasatinib | 43.03 | 13.3 | 0.7522 | 3.8263 | -0.0651 | -0.7385 | 0.5434 | 0.3324 |
| MCF 10A-H2B-mCherry | Alpelisib | 31.92 | 13.3 | Inf | 48.0469 | 0.6505 | -0.3257 | 0.5441 | 0.0840 |
| MCF 10A-H2B-mCherry | Palbociclib | 16.73 | 13.3 | 0.0533 | 0.0647 | 0.0467 | -0.0559 | 0.5491 | 0.5897 |
| MCF 10A-H2B-mCherry | Alpelisib | 20.81 | 13.3 | 15.1045 | 119.1663 | 0.5557 | -1.0000 | 0.5491 | 0.1104 |
| MCF 10A-H2B-mCherry | Alpelisib | 40.81 | 13.3 | 42.2866 | 311.4568 | 0.7077 | -1.0000 | 0.5651 | 0.0697 |
| MCF 10A-H2B-mCherry | Dasatinib | 27.48 | 13.3 | 0.3676 | 0.6715 | -0.0294 | -0.2072 | 0.5849 | 0.3882 |
| MCF 10A-H2B-mCherry | Alpelisib | 16.73 | 13.3 | 19.6489 | 124.3425 | 0.6341 | -0.9991 | 0.5951 | 0.0849 |
| MCF 10A-H2B-mCherry | Alpelisib | 29.70 | 13.3 | 27.7483 | 154.7888 | 0.6373 | -0.8744 | 0.6097 | 0.0762 |
| MCF 10A-H2B-mCherry | Palbociclib | 34.14 | 13.3 | 0.3733 | 0.7332 | -0.0259 | -0.2347 | 0.6336 | 0.3892 |