LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)
Data Columns
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- 10 Data Columns
| Name | Description | Display Name | Data Type | Unit | Precision | Readout Type | Replicate | Comments |
|---|---|---|---|---|---|---|---|---|
| cell | Cell reagent | Cell | cell | |||||
| smallMolecule | Small molecule perturbagen | Small Molecule | small_molecule | |||||
| timePointHr | End time point of rolling window (in hr; averaged across technical replicates) | Time Point (hr) | Numeric | hr | 2 | |||
| timeIntervalHr | Total time from start to end of rolling window (in hr; averaged across technical replicates) | Time Interval (hr) | Numeric | hr | 1 | |||
| gR50 | Small molecule concentration in uM at which GR(c)=0.5 | GR50 | Text | |||||
| gEC50 | Small molecule concentration in uM that results in 50% efficacy | GEC50 | Text | |||||
| gRmax | Normalized growth inhibition rate at the highest tested concentration | GRmax | Numeric | 4 | ||||
| gRinf | Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the dose-response data | GRinf | Numeric | 4 | ||||
| gRHillCoefficient | Maximal slope of the dose-response curve | GR Hill Coefficient | Numeric | 4 | ||||
| gRAOC | Integral of GR(c) over the range of concentrations tested | GR_AOC | Numeric | 4 |
- 10 Data Columns