LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Palbociclib | 16.73 | 13.3 | 0.0533 | 0.0647 | 0.0467 | -0.0559 | 0.5491 | 0.5897 |
| MCF 10A-H2B-mCherry | Palbociclib | 18.59 | 13.3 | 0.0539 | 0.0586 | 0.0305 | -0.0240 | 0.8136 | 0.5912 |
| MCF 10A-H2B-mCherry | Palbociclib | 20.81 | 13.3 | 0.0818 | 0.0973 | 0.0125 | -0.0498 | 0.9548 | 0.5611 |
| MCF 10A-H2B-mCherry | Palbociclib | 23.04 | 13.3 | 0.1204 | 0.1276 | -0.0121 | -0.0170 | 1.1476 | 0.5097 |
| MCF 10A-H2B-mCherry | Palbociclib | 25.25 | 13.3 | 0.1666 | 0.1855 | -0.0335 | -0.0382 | 1.0133 | 0.4711 |
| MCF 10A-H2B-mCherry | Palbociclib | 27.48 | 13.3 | 0.2351 | 0.2704 | -0.0078 | -0.0528 | 0.9324 | 0.4327 |
| MCF 10A-H2B-mCherry | Palbociclib | 29.70 | 13.3 | 0.3052 | 0.4586 | -0.0113 | -0.1395 | 0.8212 | 0.4077 |
| MCF 10A-H2B-mCherry | Palbociclib | 31.92 | 13.3 | 0.373 | 0.8413 | -0.0169 | -0.2786 | 0.6708 | 0.3931 |
| MCF 10A-H2B-mCherry | Palbociclib | 34.14 | 13.3 | 0.3733 | 0.7332 | -0.0259 | -0.2347 | 0.6336 | 0.3892 |
| MCF 10A-H2B-mCherry | Palbociclib | 36.36 | 13.3 | 0.3444 | 0.4474 | -0.0097 | -0.0958 | 0.6863 | 0.3906 |
| MCF 10A-H2B-mCherry | Palbociclib | 38.59 | 13.3 | 0.31 | 0.29 | 0.0116 | 0.0296 | 0.9070 | 0.3835 |
| MCF 10A-H2B-mCherry | Palbociclib | 40.81 | 13.3 | 0.3019 | 0.2687 | 0.0113 | 0.0663 | 1.1591 | 0.3735 |
| MCF 10A-H2B-mCherry | Palbociclib | 43.03 | 13.3 | 0.3121 | 0.2618 | 0.0068 | 0.1104 | 1.4192 | 0.3456 |
| MCF 10A-H2B-mCherry | Palbociclib | 45.25 | 13.3 | 0.4306 | 0.3753 | 0.0172 | 0.0899 | 1.4590 | 0.3094 |
| MCF 10A-H2B-mCherry | Palbociclib | 47.47 | 13.3 | 0.5861 | 0.5407 | 0.0540 | 0.0586 | 1.4383 | 0.2850 |
| MCF 10A-H2B-mCherry | Palbociclib | 49.69 | 13.3 | 0.8292 | 0.951 | 0.0277 | -0.0556 | 1.2258 | 0.2703 |
| MCF 10A-H2B-mCherry | Palbociclib | 51.92 | 13.3 | 1.0693 | 1.3724 | 0.0772 | -0.1087 | 1.1292 | 0.2507 |
| MCF 10A-H2B-mCherry | Palbociclib | 54.14 | 13.3 | 1.2363 | 2.3521 | 0.0194 | -0.3506 | 0.9829 | 0.2384 |
| MCF 10A-H2B-mCherry | Palbociclib | 56.36 | 13.3 | 1.3646 | 2.1723 | 0.0395 | -0.2475 | 1.0052 | 0.2296 |
| MCF 10A-H2B-mCherry | Palbociclib | 58.58 | 13.3 | 1.3483 | 1.7677 | 0.0272 | -0.1459 | 0.9164 | 0.2209 |
| MCF 10A-H2B-mCherry | Palbociclib | 60.80 | 13.3 | 1.6276 | 2.6679 | -0.0074 | -0.2749 | 0.8841 | 0.2022 |
| MCF 10A-H2B-mCherry | Palbociclib | 63.02 | 13.3 | 1.6501 | 2.7465 | -0.0209 | -0.2830 | 0.8718 | 0.2006 |
| MCF 10A-H2B-mCherry | Palbociclib | 65.24 | 13.3 | 1.9881 | 6.2593 | -0.0570 | -0.7577 | 0.8015 | 0.1967 |
| MCF 10A-H2B-mCherry | Palbociclib | 67.47 | 13.3 | 2.3141 | 4.1619 | 0.0014 | -0.4295 | 1.0422 | 0.1732 |
| MCF 10A-H2B-mCherry | Palbociclib | 69.71 | 13.4 | 3.1977 | 5.394 | -0.0186 | -0.4657 | 1.2682 | 0.1393 |