LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 66.70 | 19.50 | 1140 | 5728 | 0.2037 | 0.6310 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 68.70 | 19.50 | 1145 | 5743 | 0.2037 | 0.6329 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 70.70 | 19.50 | 1153 | 5784 | 0.2027 | 0.6343 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 72.60 | 19.50 | 1149 | 5854 | 0.1986 | 0.6304 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 74.60 | 19.50 | 1153 | 5927 | 0.1968 | 0.6303 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 76.60 | 19.50 | 1162 | 5898 | 0.1984 | 0.6340 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 78.50 | 19.50 | 1163 | 5949 | 0.1969 | 0.6333 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 80.50 | 19.50 | 1171 | 6018 | 0.1957 | 0.6332 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 82.50 | 19.50 | 1176 | 6031 | 0.1959 | 0.6339 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 84.40 | 19.50 | 1169 | 6038 | 0.1943 | 0.6331 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 86.40 | 19.50 | 1182 | 6081 | 0.1948 | 0.6348 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 88.40 | 19.50 | 1174 | 6064 | 0.1937 | 0.6333 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 90.40 | 19.50 | 1174 | 6097 | 0.1925 | 0.6333 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 92.30 | 19.50 | 1186 | 6153 | 0.1927 | 0.6347 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 94.30 | 19.50 | 1198 | 6154 | 0.1944 | 0.6372 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.70 | 19.50 | 211 | 163 | 1.2850 | 0.5969 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 4.60 | 19.50 | 318 | 295 | 1.0814 | 0.4976 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 6.60 | 19.50 | 382 | 390 | 0.9785 | 0.4861 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 8.60 | 19.50 | 449 | 442 | 1.0149 | 0.5713 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 10.60 | 19.50 | 524 | 467 | 1.1228 | 0.6550 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 12.50 | 19.50 | 590 | 495 | 1.1912 | 0.6737 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 14.50 | 19.50 | 639 | 537 | 1.1882 | 0.6727 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 16.50 | 19.50 | 702 | 626 | 1.1323 | 0.6641 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 18.40 | 19.50 | 800 | 775 | 1.0393 | 0.6847 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 20.40 | 19.50 | 877 | 951 | 0.9334 | 0.6577 |