LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 16.50 | 19.50 | 610 | 626 | 0.9728 | 0.7282 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 18.40 | 19.50 | 688 | 775 | 0.8893 | 0.7671 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 20.40 | 19.50 | 756 | 951 | 0.7977 | 0.7603 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 22.40 | 19.50 | 788 | 1150 | 0.6866 | 0.7403 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 24.30 | 19.50 | 791 | 1322 | 0.5983 | 0.7135 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 26.30 | 19.50 | 804 | 1491 | 0.5390 | 0.7086 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 28.30 | 19.50 | 815 | 1665 | 0.4895 | 0.7024 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 30.30 | 19.50 | 823 | 1887 | 0.4365 | 0.6789 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 32.20 | 19.50 | 840 | 2123 | 0.3960 | 0.6669 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 34.20 | 19.50 | 923 | 2452 | 0.3758 | 0.6859 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 36.20 | 19.50 | 947 | 2641 | 0.3582 | 0.6824 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 38.10 | 19.50 | 950 | 2867 | 0.3311 | 0.6672 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 40.10 | 19.50 | 962 | 3104 | 0.3098 | 0.6628 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 42.10 | 19.50 | 974 | 3461 | 0.2811 | 0.6539 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 44.00 | 19.50 | 981 | 3824 | 0.2562 | 0.6405 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 46.00 | 19.50 | 1004 | 4146 | 0.2423 | 0.6333 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 48.00 | 19.50 | 1054 | 4441 | 0.2379 | 0.6342 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 50.00 | 19.50 | 1089 | 4744 | 0.2305 | 0.6358 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 51.90 | 19.50 | 1094 | 4974 | 0.2216 | 0.6320 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 53.90 | 19.50 | 1104 | 5154 | 0.2168 | 0.6287 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 55.90 | 19.50 | 1112 | 5348 | 0.2122 | 0.6281 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 57.80 | 19.50 | 1117 | 5483 | 0.2094 | 0.6259 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 59.80 | 19.50 | 1117 | 5578 | 0.2058 | 0.6243 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 62.80 | 19.50 | 1132 | 5586 | 0.2078 | 0.6295 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 64.70 | 19.50 | 1127 | 5643 | 0.2051 | 0.6286 |