LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 59.80 | 19.50 | 897 | 5578 | 0.1593 | 0.5616 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 62.80 | 19.50 | 898 | 5586 | 0.1591 | 0.5622 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 64.70 | 19.50 | 893 | 5643 | 0.1566 | 0.5610 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 66.70 | 19.50 | 901 | 5728 | 0.1556 | 0.5599 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 68.70 | 19.50 | 900 | 5743 | 0.1554 | 0.5602 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 70.70 | 19.50 | 900 | 5784 | 0.1543 | 0.5590 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 72.60 | 19.50 | 922 | 5854 | 0.1566 | 0.5610 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 74.60 | 19.50 | 903 | 5927 | 0.1511 | 0.5555 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 76.60 | 19.50 | 908 | 5898 | 0.1531 | 0.5586 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 78.50 | 19.50 | 900 | 5949 | 0.1504 | 0.5569 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 80.50 | 19.50 | 915 | 6018 | 0.1513 | 0.5589 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 82.50 | 19.50 | 897 | 6031 | 0.1480 | 0.5549 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 84.40 | 19.50 | 927 | 6038 | 0.1532 | 0.5589 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 86.40 | 19.50 | 931 | 6081 | 0.1528 | 0.5593 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 88.40 | 19.50 | 906 | 6064 | 0.1493 | 0.5543 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 90.40 | 19.50 | 907 | 6097 | 0.1489 | 0.5534 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 92.30 | 19.50 | 911 | 6153 | 0.1483 | 0.5539 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 94.30 | 19.50 | 906 | 6154 | 0.1478 | 0.5544 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 2.70 | 19.50 | 325 | 163 | 2.0301 | 0.7639 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 4.60 | 19.50 | 414 | 295 | 1.4225 | 0.5343 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 6.60 | 19.50 | 464 | 390 | 1.1895 | 0.4707 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 8.60 | 19.50 | 493 | 442 | 1.1153 | 0.4742 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 10.60 | 19.50 | 513 | 467 | 1.0968 | 0.5195 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.50 | 19.50 | 531 | 495 | 1.0733 | 0.5758 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 14.50 | 19.50 | 558 | 537 | 1.0399 | 0.6174 |